anti-PIST Antibody

• Catalog number
  3631
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  PIST Antibody: Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components and is negatively regulated by TOR (Target of rapamycin). PIST, a PDZ-containing protein, was discovered in a yeast two-hybrid system as a binding partner to Beclin-1, a Bcl-2-interacting protein homologous to the yeast autophagy gene apg6. Experiments with mutant PIST proteins lacking the PDZ domain showed that PIST interaction with Beclin-1 through its coiled-coil domain can modulate Beclin-1 activity and suggest that PIST interactions with other proteins through its PDZ domain may regulate the activity of PIST and Beclin-1.
• Gene names
  PIST Antibody: CAL, FIG, PIST, GOPC1, dJ94G16.2, CAL, Golgi-associated PDZ and coiled-coil motif-containing protein, CFTR-associated ligand
• Antibodie s label
  unlabelled serum
• Purity
  PIST Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  PIST antibody was made against a 16 amino acid synthetic peptide from near the carboxy terminus of human PIST.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  PIST antibody can be used for the detection of PIST by Western blot at 1 - 4 ug/mL. Antibody can also be used for immunohistochemistry starting at 1 ug/mL. For immunofluorescence start at 10 ug/mL.
• Suspention pH azide
  PIST Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  PIST antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  9837431
• Ncbi nr
  AAG00572
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  57120
• GENE symbol
  GOPC
• Antigene name
  golgi associated PDZ and coiled-coil motif containing
• Source
  Homo sapiens
• Protein nr
  Q9HD26
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PIST  
• Gene symbol
  GOPC
• Short name
  anti-PIST Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toPIST (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:17643
• Gene
  GOPC
• Long gene name
  golgi associated PDZ and coiled-coil motif containing
• Synonyms
  • dJ94G16.2
  • PIST
  • FIG
  • GOPC1
  • CAL
• GenBank acession
  • AF287894
• Locus
  6q22.1
• Discovery year
  2003-08-29
• Entrez gene record
  57120
• Pubmed identfication
  • 11162552
  • 11520064
• RefSeq identity
  • NM_020399
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000015457

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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