anti-PICALM Antibody

• Catalog number
  5553
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  PICALM Antibody: PICALM, also known as the clathrin assembly lymphoid myeloid leukemia (CALM) protein, co-localizes with clathrin at clathrin-coated areas of the plasma membrane and in the Golgi area, and is thought to be an important component of the coated pit internalization machinery. Fusion proteins involving PICALM have been implicated in acute myeloid and T-cell acute lymphoblastic leukemia. PICALM is also expressed in neurons and is present at the synapse where it facilitates the endocytosis of the synaptic vesicle protein VAMP2. Recent studies have identified variants of PICALM associated with Alzheimer's disease and have suggested this protein may play a role in the endocytosis and recycling of the amyloid protein precursor (APP).
• Gene names
  PICALM Antibody: LAP, CALM, CLTH, Phosphatidylinositol-binding clathrin assembly protein, Clathrin assembly lymphoid myeloid leukemia protein
• Antibodie s label
  unlabelled serum
• Purity
  PICALM Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  PICALM antibody was made against a 15 amino acid synthetic peptide from near the amino terminus of human PICALM.
• Immuno application
  ELISA, Western Blot, immuno fluorescence
• Antibody advice
  PICALM antibody can be used for detection of PICALM by Western blot at 1 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  PICALM Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  PICALM antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  56788366
• Ncbi nr
  NP_009097
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  8301
• GENE symbol
  PICALM
• Antigene name
  phosphatidylinositol binding clathrin assembly protein
• Source
  Homo sapiens
• Protein nr
  Q13492
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  PICALM  
• Gene symbol
  PICALM
• Short name
  anti-PICALM Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody tophosphatidylinositol binding clathrin assembly protein (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  phosphatidylinositol binding clathrin assembly protein, CALM and CLTH and LAP, PICALM and IDBG-66712 and ENSG00000073921 and 8301, clathrin adaptor activity, nuclei, Picalm and IDBG-198693 and ENSMUSG00000039361 and 233489, PICALM and IDBG-641926 and ENSBTAG00000001657 and 513579

Gene info

• Identity
  HGNC:15514
• Gene
  PICALM
• Long gene name
  phosphatidylinositol binding clathrin assembly protein
• Synonyms
  • CALM
  • CLTH
• GenBank acession
  • BC048259
• Locus
  11q14.2
• Discovery year
  2001-04-06
• Entrez gene record
  8301
• Pubmed identfication
  • 8643484
• RefSeq identity
  • NM_007166
• VEGA ID
  OTTHUMG00000166981

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products