anti-PANX1 Antibody
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Catalog number7097
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoPANX1 Antibody: The pannexin gene family encodes a second class of putative gap junction proteins and are highly conserved in invertebrates and mammals. Pannexins (Panx) are four-pass transmembrane proteins that oligomerize to form large pore ion and metabolite-permeable channels. Pannexin-1 (PANX1) and Pannexin-3 are closely related, while Pannexin-2 is a more distant relation. PANX1 is a transmembrane protein that forms a mechanosensitive ATP-permeable channel between adjacent cells and in the endoplasmic reticulum. PANX1 may play a role as a Ca2+ -leak channel to regulate ER Ca2+ homeostasis and regulates neural stem and progenitor cell proliferation.
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Gene namesPANX1 Antibody: PX1, MRS1, UNQ2529, UNQ2529/PRO6028, Pannexin-1
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Antibodie s labelunlabelled serum
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PurityPANX1 Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toTwo transcript variants encoding different isoforms have been found for this gene.
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AntigenRabbit polyclonal PANX1 antibody was made against a 17 amino acid peptide near the amino terminus of human PANX1.
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Immuno applicationELISA, Western Blot, immuno fluorescence
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Antibody advicePANX1 antibody can be used for detection of PANX1 by Western blot at 1 - 2 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azidePANX1 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atPANX1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr39995064
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Ncbi nrNP_056183
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KDa47 kDa
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr24145
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GENE symbolPANX1
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Antigene namepannexin 1
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Sourcehomo sapiens
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Protein nrQ96RD7
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPANX1
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Short nameanti-PANX1 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toPANX1 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetpannexin 1, MRS1 and PX1 and UNQ2529, PANX1 and IDBG-68155 and ENSG00000110218 and 24145, scaffold protein binding, Cell surfaces, Panx1 and IDBG-134948 and ENSMUSG00000031934 and 55991, PANX1 and IDBG-641615 and ENSBTAG00000012010 and 528169
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Gene info
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Identity
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Gene
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Long gene namepannexin 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2000-07-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Pannexins
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data