anti Neuregulin Heregulin 1β Antibody

anti Neuregulin Heregulin 1β Antibody is available 2 times from Biovision labs

  • This antibody has been succesfully tested for use in following methods:
    Western blot
  • Target of this antibody:
    Heregulin 1 beta
  • Alternative names of antibody target:
    NGR beta 1, Heregulin, HRG 1beta, Neuregulin
  • Recommended usage:
    Western blot: ~1:200
  • Storage information:
    Shelf time: 12 months in temp.: -20 deg.C
  • Shipping conditions:
    gel pack
  • Antibody host:
    Rabbit
  • This antibody reacts with:
    Human
  • Clonality of antibody:
    Polyclonal
  • Isotype:
    Rabbit IgG
  • Purification method:
    Affinity Purified Antibody
  • Immunogene sequence:
    Recombinant protein Heregulin-1 beta (177-241 aa) (BV-M66)
  • How to handle this antibody:
    The antibody solution should be gently mixed before use.
  • Background information:
    Neuregulin/Heregulin is a family of structurally related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and transmembrane proteins derived from the NRG1 gene. Proteolytic processing of the extracellular domain of the transmembrane NRG1 isoforms release soluble growth factors. HRG1-β1 contains an Ig domain and an EGF-like domain that is necessary for direct binding to receptor tyrosine kinases erb3 and erb4. This binding induces erb3 and erb4 heterodimerization with erb2, stimulating intrinsic kinase activity, which leads to tyrosine phosphorylation. Although HRG1-β1 biological effects is still unclear, it has been found to promote motility and invasiveness of breast cancer cells which may also involve up-regulation of expression and function of the autocrine motility-promoting factor (AMF). Recombinant human Heregulin-β1 (HRG1-β1) is a 7.5 kDa polypeptide consisting of only the EGF domain of Heregulin-β1 (65 amino acid residues).
  • Form of antibody:
    Liquid
  • Concentration of antibody:
    0.5 mg/ml
  • Gene target
  • Short name
    anti-Neuregulin/Heregulin-1β Antibody
  • Technique
    Antibody, anti
  • Alternative name
    antibody to-Neuregulin/Heregulin-1β (Antibody to)
  • Alternative technique
    antibodies

6650-100 | anti-Neuregulin/Heregulin-1β Antibodysize: Neuregulin/Heregulin-1β Antibody | 415.71 USD

  • Catalog number
    6650-100
  • Supplier
  • Price
    415.71 USD
  • Size
    Neuregulin/Heregulin-1β Antibody
  • Formulation of this antibody:
    100 µg (0.5 mg/ml) of antibody in PBS pH 7.2 containing 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
MeSH Data
  • Name
  • Concept
    Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    classification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
Additional information

6650-30T | anti-Neuregulin/Heregulin-1β Antibodysize: Neuregulin/Heregulin-1β Antibody | 180.8 USD

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