anti-Myogenin Antibody [5FD]

• Catalog number
  49-222
• Price
  Please ask
• Size
  0.05 mg

• Gene info
  Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80% amino acid homology in their bHLH motifs. Transfection of myogenin and other family members into a variety of non-muscle cells has been shown to either convert these cells to myogenic cells, or to transcriptionally activate a set of otherwise unexpressed muscle-specific genes. In addition to activating muscle specific genes, members of the MyoD family members activate their own transcription and transactivate the transcription of other MyoD family members. Each member of the MyoD family has distinct roles in muscle development; myogenin plays a key role in muscle maturation. Myogenin migrates at a molecular weight of ~34 kDa by SDS-PAGE. Myogenin, also known as Myf-4, is a muscle specific transcription factor that converts multipotential mesodermal cells to myoblasts and is essential for the development of functional skeletal muscle. It is a member of the basic helix-loop-helix gene family.
• Gene names
  MYOG, BHLHc3, Myogenin, MYF4, Myogenic factor 4, Myf-4, Myogenin (myogenic factor 4)
• Antibodie s label
  unlabelled serum
• Purity
  Protein G Column
• Ab raised in
  Mouse
• Type
  Monoclonal
• Monoclonal
  [5FD]
• Immunoglobulin
  IgG
• Antigen
  Myogenin monoclonal antibody was made against amino acids 30 - 224 of Myogenin (Rat).
• Immuno application
  Western Blot, immuno-histo-chemistry, immuno-cyto-chemistry
• Antibody advice
  Myogenin antibody can be used in immunohistochemistry starting at 10 ug/mL, and immunohistochemistry in frozen tissues starting at 1:50.
• Suspention pH azide
  PBS, 0.05% BSA, 0.05% sodium azide.
• Keep at
  Myogenin antibody should be stored long term (months) at -80 grades C and short term (days) at 4 grades C. As with all antibodies avoid freeze/thaw cycles.
• Works with
  Human, Mouse, Rat
• Omim nr
  127625
• Ncbi nr
  P15173
• Vial with antibody
  in solution
• NCBI GENE nr
  4656
• GENE symbol
  MYOG
• Antigene name
  myogenin (myogenic factor 4)
• Source
  Homo sapiens
• Protein nr
  P15173
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Myogenin   [5FD]  
• Short name
  anti-Myogenin Antibody [5FD]
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toMyogenin (antibody to-) [5FD]
• Alternative technique
  antibodies

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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