anti-MyD88 Antibody [2E9C2]

• Catalog number
  PM-4673
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  MyD88 Monoclonal Antibody: The pro-inflammatory cytokine IL-1 induced cellular response requires IL-1 receptor complex including IL-1RI and IL-1RAcP. MyD88 has been identified as an adapter molecule in the IL-1 signaling pathway. MyD88 associates with and recruits IRAK to the IL-1 receptor complex in response to IL-1 treatment and dominant negative form of MyD88 attenuates IL-1R-mediated NF-kB activation. MyD88 is also employed as a regulator molecule by IL-18 receptor and human Toll receptor, which are members in the Toll/IL-1R family of receptors. Targeted disruption of the MyD88 gene results in lose of cellular responses to IL-1 and IL-18, and MyD88-deficient mice lack responses to bacterial product LPS that employs Toll-like receptors 2 and 4 (TLR2 and TLR4) as the signaling receptors. MyD88 is a general adapter protein for the Toll/IL-1R family of receptors and plays an important role in the inflammatory response induced by cytokines IL-1 and IL-18 and endotoxin. MyD88 gene is expressed in many tissues.
• Gene names
  MyD88 Antibody [2E9C2] : MYD88D
• Antibodie s label
  unlabelled serum
• Purity
  MyD88 Monoclonal Antibody is immunoaffinity chromotography purified IgG.
• Ab raised in
  Mouse
• Type
  Monoclonal
• Monoclonal
  2E9C2
• Immunoglobulin
  IgG2b
• Antigen
  Mouse monoclonal MyD88 antibody was made against a recombinant protein corresponding to amino acids 176 to 280 of human MyD88.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  MyD88 antibody can be used for detection of MyD88 by Western blot at 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  MyD88 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  MyD88 monoclonal antibody can be stored at -20 grades C, stable for one year.
• Works with
  Human, Mouse
• Omim nr
  1814020
• Ncbi nr
  AAC50954
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  4615
• GENE symbol
  MYD88
• Antigene name
  myeloid differentiation primary response gene (88)
• Source
  Homo sapiens
• Protein nr
  Q99836
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MyD88   [2E9C2]  
• Short name
  anti-MyD88 Antibody [2E9C2]
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toMyD88 (antibody to-) [2E9C2]
• Alternative technique
  antibodies
• Alternative to gene target
  myeloid differentiation primary response 88, MYD88D, MYD88 and IDBG-25713 and ENSG00000172936 and 4615, TIR domain binding, Plasma membranes, Myd88 and IDBG-204565 and ENSMUSG00000032508 and 17874, MYD88 and IDBG-644299 and ENSBTAG00000000563 and 444881

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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