MYCN Antibody

• Catalog number
  F50371-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  MYCN
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the MYCN antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This MYCN antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P04198
• Purity
  Purified
• Description
  MYCN is a member of the MYC family and a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of its gene is associated with a variety of tumors, most notably neuroblastomas.
• Immunogen
  A portion of amino acids 322-351 from the human protein was used as the immunogen for this MYCN antibody.
• Storage
  Aliquot the MYCN antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MYCN  
• Gene symbol
  MYCN, MYCNOS
• Short name
  Anti-MYCN
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to MYCN
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7559
• Gene
  MYCN
• Long gene name
  MYCN proto-oncogene, bHLH transcription factor
• Synonyms gene
  • NMYC
• Synonyms gene name
  • v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
• Synonyms
  • bHLHe37
  • N-myc
  • MYCNOT
• GenBank acession
  • BC002712
• Locus
  2p24.3
• Discovery year
  2001-06-22
• Entrez gene record
  4613
• Pubmed identfication
  • 20153925
• RefSeq identity
  • NM_005378
• Classification
  • Basic helix-loop-helix proteins
• VEGA ID
  OTTHUMG00000039579

Gene info

• Identity
  HGNC:16911
• Gene
  MYCNOS
• Long gene name
  MYCN opposite strand
• Synonyms gene name
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) opposite strand
  • MYCN opposite strand/antisense RNA (non-protein coding)
  • MYCN opposite strand/antisense RNA
• Synonyms
  • NCYM
  • N-CYM
  • MYCN-AS1
• Synonyms name
  • MYCN antisense RNA 1
  • DNA binding transcriptional activator
• GenBank acession
  • S49953
• Locus
  2p24.3
• Discovery year
  2004-02-04
• Entrez gene record
  10408
• Pubmed identfication
  • 1419902
  • 24391509
  • 26156430
• RefSeq identity
  • NR_110230
• VEGA ID
  OTTHUMG00000151741

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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