Anti-Mouse CD72 is available 1 time from Reliatech antibodies labs
- Gene NameCD72
- Species ReactivityMouse (Mus musculus)
- SynonymsCd72; CD72c; Ly-19; Ly-32; Lyb-2; Ly-m19
- DescriptionThis is a highly purified antibody with strong binding affinity towards the antigen that it has been risen against.Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in.
- Storage and handlingLyophilized antibodies can be shipped at ambient temperature and stored for short terms at +4 degrees Celsius and at -20 for long term storage. Reconstituted lyophilised and antibodies in liquid form can be shipped and stored for short terms at +4 degrees Celsius. Generally, it is recomended for long term storage (up to one year) 25-50% glycerol or ethylene glycol to be added and the vial must be stored at -20°C.
- AdvisoryIn order to retain the quality and the affinity of the antibodies unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
- Additional descriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
- TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
- Latin nameMus musculus
- Gene target
- Short nameAnti-Mouse CD72
- TechniqueMouse, anti
- Alternative nameantibody to-Mouse CD72 molecule
- Alternative techniqueantibodies
- Alternative to gene targetCD72 molecule, CD72b and LYB2, CD72 and IDBG-62668 and ENSG00000137101 and 971, this GO :0004888 and transmembrane signaling receptor activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007165 and signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0030246 and carbohydrate binding and molecular function, carbohydrate binding, this GO :0004888: transmembrane signaling receptor activity and also this GO :0005102: receptor binding and also this GO :0005515: protein binding and also this GO :0030246: carbohydrate binding, this GO :0004888: transmembrane signaling receptor activity, this GO :0005102: receptor binding, this GO :0005515: protein binding, this GO :0030246: carbohydrate binding, Plasma membranes, Cd72 and IDBG-141026 and ENSMUSG00000028459 and 12517, CD72 and IDBG-633031 and ENSBTAG00000011409 and 783725
103-M344 | Anti-Mouse CD72size: 100ug | 413.82 USD
- Catalog number103-M344
- Price413.82 USD
1. Gene info
- Long gene nameCD72 molecule
- Synonyms gene name
- CD72 antigen
- Discovery year1991-10-04
- Entrez gene record
- Pubmed identfication
- RefSeq identity
- CD molecules
- C-type lectin domain containing
- Havana BLAST/BLAT
- ConceptScope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
- Tree numbers
- Qualifiersclassification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
- PubMedCD72 activates extracellular signal-regulated kinase and c-Jun N-terminal kinase (but not p38 mitogen-activated protein kinase), synergizing with B cell receptor signals to induce proliferation of B cells in X-linked immunodeficiency.Inhibitory coreceptors CD72 and CD22 are responsible for setting the requirement of CD40 signaling for survival and proliferation of antigen-stimulated spleen B cells.results strongly suggest that the apoptosis preventing signal evoked by CD72 ligation is delivered through the pathway of NF-kappaB, c-Myc, p27(Kip1) and cyclinStrength of B-cell antigen receptor signals is strictly tuned by the interaction of CD100 with CD72; this interaction is essential for maintaining immunological homeostasis as well as generating a proper immune response.CD72 plays a dominant role as a negative regulator of BCR signaling in primary mature B lymphocytes.CD72 is required to maintain B cell anergy and functions as a regulator of peripheral B cell toleranceThese results strongly suggest that the Cd72(c) is a crucial modifier gene that regulates Fas(lpr)-induced autoimmune disease due to its reduced activity of B cell signal regulation.
- Gene ontology - Cellular component
- Gene ontology - Molecular function
- Entrez Gene
Supplier:Bioss Primary Unconjugated Antibodies