Anti Mouse CD105 Endoglin
Anti Mouse CD105 Endoglin is available 10 times from Reliatech antibodies labs
- Gene NameCD105/Endoglin
- Species ReactivityMouse (Mus musculus)
- DescriptionThis is a highly purified antibody with strong binding affinity towards the antigen that it has been risen against.Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in.
- Storage and handlingLyophilized antibodies can be shipped at ambient temperature and stored for short terms at +4 degrees Celsius and at -20 for long term storage. Reconstituted lyophilised and antibodies in liquid form can be shipped and stored for short terms at +4 degrees Celsius. Generally, it is recomended for long term storage (up to one year) 25-50% glycerol or ethylene glycol to be added and the vial must be stored at -20°C.
- AdvisoryIn order to retain the quality and the affinity of the antibodies unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
- Additional descriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
- TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
- Latin nameMus musculus
- Gene target
- Short nameAnti-Mouse CD105/Endoglin
- TechniqueMouse, anti
- Alternative nameantibody to-Mouse CD105/Endoglin
- Alternative techniqueantibodies
103-PA60 | Anti-Mouse CD105/Endoglinsize: 200ug | 244.79 USD
103-M60-FITC | Anti-Mouse CD105/Endoglinsize: 50ug | 292.76 USD
103-PA60AG | Anti-Mouse CD105/Endoglinsize: 50ug | 221.42 USD
103-M60S-PE | Anti-Mouse CD105/Endoglinsize: 25ug | 189.44 USD
103-MBi60 | Anti-Mouse CD105/Endoglinsize: 50ug | 292.76 USD
103-M60 | Anti-Mouse CD105/Endoglinsize: 100ug | 292.76 USD
103-M102 | Anti-Mouse CD105/Endoglinsize: 200ug | 621.2 USD
103-PA60S | Anti-Mouse CD105/Endoglinsize: 100ug | 180.82 USD
103-M60S-FITC | Anti-Mouse CD105/Endoglinsize: 25ug | 189.44 USD
103-M60-PE | Anti-Mouse CD105/Endoglinsize: 50ug | 292.76 USD
- Catalog number103-M60-PE
- Price292.76 USD
1. Gene info
- Long gene nameendoglin
- Synonyms gene
- Synonyms gene name
- Osler-Rendu-Weber syndrome 1
- GenBank acession
- Discovery year1993-03-03
- Entrez gene record
- Pubmed identfication
- CD molecules
- Havana BLAST/BLAT
- Locus Specific Databases
- ConceptScope note:Technique using an instrument system for making, processing, and displaying one or more measurements on individual cells obtained from a cell suspension. Cells are usually stained with one or more fluorescent dyes specific to cell components of interest, e.g., DNA, and fluorescence of each cell is measured as it rapidly transverses the excitation beam (laser or mercury arc lamp). Fluorescence provides a quantitative measure of various biochemical and biophysical properties of the cell, as well as a basis for cell sorting. Other measurable optical parameters include light absorption and light scattering, the latter being applicable to the measurement of cell size, shape, density, granularity, and stain uptake.
- Tree numbers
- Qualifiersclassification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
- PubMedEndoglin promotes transforming growth factor beta-mediated Smad 1/5/8 signaling and inhibits endothelial cell migration through its association with GIPCthe TGFbeta1 coreceptor Eng selectively regulates expression of multiple transient receptor potential channels in the setting of left or right ventricular pressure overloadData suggest that excessive vascular endothelial growth factor stimulation may play a role in the initiation and development of brain vessel malformations in states of relative endoglin insufficiency in adulthood.Eng was more widely expressed than Acvrl1 in lungs. Eng alone was found in pulmonary veins, potentially explaining increased frequency of arteriovenous malformations in hereditary haemorrhagic telangiectasia.Age-associated pulmonary vascular eNOS uncoupling may explain the late childhood and adult onset of clinical lung manifestations.We propose that endoglin regulates primitive hematopoiesis by modulating the activity of the Smad1/5 signaling pathway in early stages of developmentThus, endoglin haploinsufficiency seems to promote fibroblast accumulation during wound healing through the activation of the PI3K/Akt pathway.
- Gene ontology - Biological processpositive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
- Gene ontology - Cellular component
- Gene ontology - Molecular function
- Entrez Gene
Supplier:Bioss Polyclonal Antibodies