LXR Antibody

• Catalog number
  3641-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  LXR
• Target Alternative Name
  LXRA , NR1H3 , Liver X receptor alpha , LXR a , Oxysterols receptor
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 435 of human LXR
• Accession
  Q13133
• Gene Id
  10062
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  0.5 mg/ml affinity purified rabbit anti-LXR polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Other applications have not been determined. The antibody detects 49 kDa LXR alpha and beta subunits of human, mouse, rat and bovine LXR. Cross-reactivity to other species has not been determined. Jurkat cell lysate (Cat.# 2401-100) and mouse small intestine tissue lysate (Cat.# 2601-100) can be used as positive controls.
• Description
  Liver X receptors (LXRs) are oxysterol activated nuclear receptors which are involved in the regulation of genesis and metabolism of cholesterols and bile acids. LXRs form heterodimeric complexes with the retinoic acid receptors (RARs) once activated by their respective oxysterol ligands. Two known isoforms, alpha and beta, are differentially expressed; the alpha isoform predominantly expressed in liver, whereas beta isoform expression has been shown to be ubiquitous.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  LXR  
• Gene symbol
  NR1H3, NR1H2
• Short name
  LXR Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  LXR (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:7966
• Gene
  NR1H3
• Long gene name
  nuclear receptor subfamily 1 group H member 3
• Synonyms gene name
  • nuclear receptor subfamily 1, group H, member 3
• Synonyms
  • LXR-a
  • RLD-1
  • LXRa
• Synonyms name
  • liver X receptor-alpha
• GenBank acession
  • U22662
• Locus
  11p11.2
• Discovery year
  1999-09-17
• Entrez gene record
  10062
• Pubmed identfication
  • 8621574
  • 7744246
• Classification
  • Nuclear receptor subfamily 1 group H
• VEGA ID
  OTTHUMG00000150628

Gene info

• Identity
  HGNC:7965
• Gene
  NR1H2
• Long gene name
  nuclear receptor subfamily 1 group H member 2
• Synonyms gene
  • UNR
• Synonyms gene name
  • ubiquitously-expressed nuclear receptor
  • nuclear receptor subfamily 1, group H, member 2
• Synonyms
  • NER
  • NER-I
  • RIP15
  • LXR-b
  • LXRb
• Synonyms name
  • liver X receptor-beta
• GenBank acession
  • U14534
• Locus
  19q13.3
• Discovery year
  1994-09-19
• Entrez gene record
  7376
• Pubmed identfication
  • 7782080
  • 7971966
• Classification
  • Nuclear receptor subfamily 1 group H
• VEGA ID
  OTTHUMG00000183036

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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