anti-LGI3 Antibody

• Catalog number
  4493
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  LGI3 Antibody: The leucine-rich, glioma inactivated gene 3 (LGI3) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI3 have not been found to be associated with ADTLE. LGI3 expression is induced in rat astrocyte cultures by the amyloid beta (Abeta) peptide and accumulated on neuronal plasma membranes of aged monkey brains and co-localized with Abeta.
• Gene names
  LGI3 Antibody: LGIL4, LGIL4, UNQ8190/PRO23199, Leucine-rich repeat LGI family member 3, LGI1-like protein 4
• Antibodie s label
  unlabelled serum
• Purity
  LGI3 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  Two isoforms of LGI3 are known to exist; this LGI3 antibody will recognize both. This LGI3 antibody is predicted to be specific to LGI3 and not recognize other LGI proteins. The observed higher molecular weight band may represent a post-translationally modified form of LGI3.
• Antigen
  LGI3 antibody was made against a 12 amino acid synthetic peptide from near the center of human LGI3.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  LGI3 antibody can be used for the detection of LGI3 by Western blot at 1 ug/mL.
• Suspention pH azide
  LGI3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  LGI3 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  37181338
• Ncbi nr
  AAQ88483
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  203190
• GENE symbol
  LGI3
• Antigene name
  leucine-rich repeat LGI family, member 3
• Source
  Homo sapiens
• Protein nr
  Q8N145
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  LGI3  
• Gene symbol
  LGI3
• Short name
  anti-LGI3 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toLGI3 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  leucine-rich repeat LGI family, member 3, LGI3 and IDBG-10343 and ENSG00000168481 and 203190, protein binding, Extracellular, Lgi3 and IDBG-178840 and ENSMUSG00000033595 and 213469, LGI3 and IDBG-634665 and ENSBTAG00000004578 and 516661

Gene info

• Identity
  HGNC:18711
• Gene
  LGI3
• Long gene name
  leucine rich repeat LGI family member 3
• Synonyms gene name
  • leucine-rich repeat LGI family, member 3
• GenBank acession
  • AJ487518
• Locus
  8p21.3
• Discovery year
  2002-05-30
• Entrez gene record
  203190
• Pubmed identfication
  • 12023020
  • 18628660
• Classification
  • LGI family
• VEGA ID
  OTTHUMG00000131599

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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