anti-LGI3 Antibody
#
-
Catalog number4493
-
Price:
-
Size0.02 mg, 0.1 mg
-
-
Gene infoLGI3 Antibody: The leucine-rich, glioma inactivated gene 3 (LGI3) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI3 have not been found to be associated with ADTLE. LGI3 expression is induced in rat astrocyte cultures by the amyloid beta (Abeta) peptide and accumulated on neuronal plasma membranes of aged monkey brains and co-localized with Abeta.
-
Gene namesLGI3 Antibody: LGIL4, LGIL4, UNQ8190/PRO23199, Leucine-rich repeat LGI family member 3, LGI1-like protein 4
-
Antibodie s labelunlabelled serum
-
PurityLGI3 Antibody is affinity chromatography purified via peptide column.
-
Ab raised inRabbit
-
TypePolyclonal
-
ImmunoglobulinIgG
-
Spicific toTwo isoforms of LGI3 are known to exist; this LGI3 antibody will recognize both. This LGI3 antibody is predicted to be specific to LGI3 and not recognize other LGI proteins. The observed higher molecular weight band may represent a post-translationally modified form of LGI3.
-
AntigenLGI3 antibody was made against a 12 amino acid synthetic peptide from near the center of human LGI3.
-
Immuno applicationELISA, Western Blot
-
Antibody adviceLGI3 antibody can be used for the detection of LGI3 by Western blot at 1 ug/mL.
-
Suspention pH azideLGI3 Antibody is supplied in PBS containing 0.02% sodium azide.
-
Keep atLGI3 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
-
Works withHuman, Mouse, Rat
-
Omim nr37181338
-
Ncbi nrAAQ88483
-
Vial with antibodyin solution
-
Quantity per ml1 mg/mL
-
NCBI GENE nr203190
-
GENE symbolLGI3
-
Antigene nameleucine-rich repeat LGI family, member 3
-
SourceHomo sapiens
-
Protein nrQ8N145
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolLGI3
-
Short nameanti-LGI3 Antibody
-
TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
-
Alternative nameAntibody toLGI3 (antibody to-)
-
Alternative techniqueantibodies
-
Alternative to gene targetleucine-rich repeat LGI family, member 3, LGI3 and IDBG-10343 and ENSG00000168481 and 203190, protein binding, Extracellular, Lgi3 and IDBG-178840 and ENSMUSG00000033595 and 213469, LGI3 and IDBG-634665 and ENSBTAG00000004578 and 516661
-
Gene info
-
Identity
-
Gene
-
Long gene nameleucine rich repeat LGI family member 3
-
Synonyms gene name
- leucine-rich repeat LGI family, member 3
-
GenBank acession
-
Locus
-
Discovery year2002-05-30
-
Entrez gene record
-
Pubmed identfication
-
Classification
- LGI family
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data