anti-LEMD3 Antibody

• Catalog number
  6603
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  LEMD3 Antibody: LEMD3 (LEM domain-containing 3) is a lem-domain containing protein, also known as MAN1, whose loss of function results in disorders characterized by osteopoikilosis, Buschke-Ollendorff syndrome, and melorheostosis. LEMD3 is an inner nuclear membrane protein that interacts with BMP and activin-TGF-beta receptor-activated Smads and antagonizes TGF-beta signaling in human cells.
• Gene names
  LEMD3 Antibody: MAN1, MAN1, Inner nuclear membrane protein Man1, LEM domain-containing protein 3
• Antibodie s label
  unlabelled serum
• Purity
  LEMD3 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  At least three isoforms of LEMD3 are known to exist; this antibody will detect all isoforms. LEMD3 antibody is predicted to not cross-react with LEMD1 and LEMD2
• Antigen
  LEMD3 antibody was made against an 18 amino acid synthetic peptide near the carboxy terminus of human LEMD3.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  LEMD3 antibody can be used for detection of LEMD3 by Western blot at 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 5 ug/mL.
• Suspention pH azide
  LEMD3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  LEMD3 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse
• Omim nr
  7706607
• Ncbi nr
  NP_055134
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  23592
• GENE symbol
  LEMD3
• Antigene name
  LEM domain containing 3
• Source
  Homo sapiens
• Protein nr
  Q9Y2U8
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  LEMD3  
• Gene symbol
  LEMD3
• Short name
  anti-LEMD3 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toLEMD3 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  LEM domain containing 3, MAN1, LEMD3 and IDBG-45263 and ENSG00000174106 and 23592, protein binding, nuclei, Lemd3 and IDBG-192717 and ENSMUSG00000048661 and 380664, LEMD3 and IDBG-634335 and ENSBTAG00000039435 and 530659

Gene info

• Identity
  HGNC:28887
• Gene
  LEMD3
• Long gene name
  LEM domain containing 3
• Synonyms
  • MAN1
• Synonyms name
  • inner nuclear membrane protein Man1
  • MAN antigen 1
• GenBank acession
  • AF263918
• Locus
  12q14.3
• Discovery year
  2004-11-01
• Entrez gene record
  23592
• Pubmed identfication
  • 10671519
  • 15489854
• Classification
  • LEM domain containing
• VEGA ID
  OTTHUMG00000168840

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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