anti-KREMEN2 Antibody

• Catalog number
  7263
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  KREMEN2 Antibody: Kremen (Kringle containing protein marking the eye and the nose) proteins are type I transmembrane proteins that contain extracellular kringle, WSC and CUB domains and an intracellular region without any conserved motifs. Kremens bind a subset of the secreted Dickkopf proteins (Dkk 1, 2, and 4) with high affinity to modulate the canonical Wnt signaling pathway that is transduced by the ternary receptor complex composed of Wnt, Frizzled, and the LDL receptor related protein 5/6 (LRP5/6) co-receptor. Recent experiments have shown that KREMEN2 is a regulator of bone remodeling and raise the possibility that antagonizing KREMEN2 might prove beneficial in patients with bone loss disorders.
• Gene names
  KREMEN2 Antibody: KRM2, KRM2, Kremen protein 2, Dickkopf receptor 2
• Antibodie s label
  unlabelled serum
• Purity
  KREMEN2 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  Multiple isoforms of KREMEN2 are known to exist. KREMEN2 antibody is predicted to not cross-react with other Kremen protein family members.
• Antigen
  KREMEN2 antibody was made against a 15 amino acid peptide near the carboxy terminus of human KREMEN2 .
• Immuno application
  ELISA, Western Blot, immuno-cyto-chemistry
• Antibody advice
  KREMEN2 Antibody can be used for detection of KREMEN2 by Western blot starting at 1 ug/mL.
• Suspention pH azide
  KREMEN2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  KREMEN2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
• Works with
  Human, Mouse
• Omim nr
  27437008
• Ncbi nr
  NP_757384
• KDa
  Predicted: 51 kDa Observed: 54 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  79412
• GENE symbol
  KREMEN2
• Antigene name
  kringle containing transmembrane protein 2
• Source
  homo sapiens
• Protein nr
  Q8NCW0
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  KREMEN2  
• Gene symbol
  KREMEN2
• Short name
  anti-KREMEN2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toKREMEN2 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18797
• Gene
  KREMEN2
• Long gene name
  kringle containing transmembrane protein 2
• Synonyms
  • MGC10791
  • KRM2
• GenBank acession
  • BC003533
• Locus
  16p13.3
• Discovery year
  2002-06-20
• Entrez gene record
  79412
• Pubmed identfication
  • 12050670
• RefSeq identity
  • NM_145347
• VEGA ID
  OTTHUMG00000128976

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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