anti-KappaB ras Antibody

  • Catalog number
    2491
  • Price
    Please ask
  • Size
    0.02 mg, 0.1 mg
  • Gene info
    KappaB ras Antibody: KappaB ras-1 (kB-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with IkB (IkB), an inhibitor of the transcription factor NF-kB. IkB exists in two homologous forms, IkB-alpha and IkB-beta, although IkB-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive IkB-alpha-NF-kB complexes can shuttle in and out of the nucleus, IkB-beta-NF-kB complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the IkB-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of IkB-beta and regulating the rate of degradation of IkB-beta. This antibody detects both kappaB-ras1 and kappaB-ras2.
  • Gene names
    KappaB ras Antibody: KBRAS1, kappaB-Ras1, KBRAS1, NF-kappa-B inhibitor-interacting Ras-like protein 1, I-kappa-B-interacting Ras-like protein 1, Kappa B-Ras protein 1
  • Antibodie s label
    unlabelled serum
  • Purity
    KappaB ras Antibody is affinity chromatography purified via peptide column.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Immunoglobulin
    IgG
  • Antigen
    KappaB ras antibody was made against a 18 amino acid synthetic peptide from near the center of human KappaB ras 1.
  • Immuno application
    ELISA, Western Blot, immuno-histo-chemistry
  • Antibody advice
    KappaB ras antibody can be used for detection of KappaB ras by Western blot at 2 - 4 ug/mL. Antibody can also be used for immunohistochemistry starting at 1 ug/mL.
  • Suspention pH azide
    KappaB ras Antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    KappaB ras antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human, Mouse, Rat
  • Omim nr
    7008402
  • Ncbi nr
    AAF34998
  • Vial with antibody
    in solution
  • NCBI GENE nr
    28512
  • GENE symbol
    NKIRAS1
  • Antigene name
    NFKB inhibitor interacting Ras-like 1
  • Source
    Homo sapiens
  • Protein nr
    Q9NYS0
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    KappaB   ras  
  • Gene symbol
    NKIRAS1, NKIRAS2
  • Short name
    anti-KappaB ras Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toKappaB ras (antibody to-)
  • Alternative technique
    antibodies
Gene info
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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