anti-KappaB ras Antibody
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Catalog number2491
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoKappaB ras Antibody: KappaB ras-1 (kB-ras-1) and kappaB-ras-2 are two small proteins that similar to Ras-like small GTPases that associate with IkB (IkB), an inhibitor of the transcription factor NF-kB. IkB exists in two homologous forms, IkB-alpha and IkB-beta, although IkB-beta contains a unique 47-amino acid region within its ankyrin domain. While inactive IkB-alpha-NF-kB complexes can shuttle in and out of the nucleus, IkB-beta-NF-kB complexes are retained exclusively in the cytoplasm. It is suggested that kappaB-ras proteins preferentially bind to the IkB-beta form through this unique insert within the ankyrin region, thus modulating the cellular location of IkB-beta and regulating the rate of degradation of IkB-beta. This antibody detects both kappaB-ras1 and kappaB-ras2.
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Gene namesKappaB ras Antibody: KBRAS1, kappaB-Ras1, KBRAS1, NF-kappa-B inhibitor-interacting Ras-like protein 1, I-kappa-B-interacting Ras-like protein 1, Kappa B-Ras protein 1
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Antibodie s labelunlabelled serum
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PurityKappaB ras Antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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AntigenKappaB ras antibody was made against a 18 amino acid synthetic peptide from near the center of human KappaB ras 1.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry
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Antibody adviceKappaB ras antibody can be used for detection of KappaB ras by Western blot at 2 - 4 ug/mL. Antibody can also be used for immunohistochemistry starting at 1 ug/mL.
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Suspention pH azideKappaB ras Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atKappaB ras antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works withHuman, Mouse, Rat
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Omim nr7008402
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Ncbi nrAAF34998
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Vial with antibodyin solution
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NCBI GENE nr28512
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GENE symbolNKIRAS1
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Antigene nameNFKB inhibitor interacting Ras-like 1
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SourceHomo sapiens
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Protein nrQ9NYS0
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolNKIRAS1, NKIRAS2
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Short nameanti-KappaB ras Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toKappaB ras (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameNFKB inhibitor interacting Ras like 1
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Synonyms gene name
- NFKB inhibitor interacting Ras-like protein 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-03-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RAS type GTPase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameNFKB inhibitor interacting Ras like 2
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Synonyms gene name
- NFKB inhibitor interacting Ras-like protein 2
- NFKB inhibitor interacting Ras-like 2
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-03-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RAS type GTPase family
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data