anti-IQSEC2 Antibody
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Catalog number8011
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoADP ribosylation factors (Arfs) are small GTP-binding proteins known for their role in vesicular transport, where they nucleate the assembly of coat protein complexes at sites of carrier vesicle formation. Similar to the related protein IQSEC1, IQSEC2 is a guanine nucleotide exchange protein for ARF1 and ARF6 that belongs to the BRAG family and contains one IQ domain, one PH domain and one SEC7 domain (1,2). IQSEC2 is a major component of the postsynaptic density (PSD) and colocalizes with PSD-95. It has been suggested to modulate the functions of the ARF proteins (1). Mutations in this gene have been implicated in nonsyndromic X-linked mental retardation (3).
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Gene namesIQ motif and Sec7 domain 2, Brefeldin-resistant Arf-GEF 1 protein, BRAG1, MRX1
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Antibodie s labelunlabelled serum
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PurityIQSEC2 antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toIQSEC2 antibody is human, mouse and rat reactive. At least two isoforms of IQSEC2 are known to exist; this antibody will only detect the larger isoform. IQSEC2 antibody is predicted to not cross-react with IQSEC1.
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AntigenIQSEC2 antibody was made against an 18 amino acid peptide near the carboxy terminus of human IQSEC2.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry
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Antibody adviceIQSEC2 antibody can be used for detection of IQSEC2 by Western blot at 1 - 2 ug/ml. Antibody can also be used for immunohistochemistry starting at 5 ug/mL.
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Suspention pH azideIQSEC2 antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atIQSEC2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
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Works withHuman, Mouse, Rat
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Omim nr162138911
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Ncbi nrNP_001104595
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KDaPredicted: 104, 133, 141, 164 kDa Observed: 140 kDa
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr23096
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GENE symbolIQSEC2
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Antigene nameIQ motif and Sec7 domain 2
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Sourcehomo sapiens
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Protein nrQ5JU85
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolIQSEC2
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Short nameanti-IQSEC2 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toIQSEC2 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameIQ motif and Sec7 domain ArfGEF 2
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Synonyms gene
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Synonyms gene name
- mental retardation, X-linked 1 (non-dysmorphic)
- mental retardation, X-linked 78
- mental retardation, X-linked 18
- IQ motif and Sec7 domain 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2004-08-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- IQSEC ArfGEF family
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
