anti-IMPDH2 Antibody

• Catalog number
  26-856
• Price
  Please ask
• Size
  50 ug

• Gene info
  IMPDH2 is the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. It catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. IMPDH2 is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation.This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
• Gene names
  IMPDH2, IMPD2, IMPDH-II
• Antibodie s label
  unlabelled serum
• Purity
  Antibody is purified by peptide affinity chromatography method.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Antigen
  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human IMPDH2.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  IMPDH2 antibody can be used for detection of IMPDH2 by ELISA at 1:312500. IMPDH2 antibody can be used for detection of IMPDH2 by western blot at 1 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
• Suspention pH azide
  Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
• Keep at
  For short periods of storage (days) store at 4 grades C. For longer periods of storage, store IMPDH2 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
• Works with
  Human, Mouse, Rat
• Omim nr
  66933016
• Ncbi nr
  NP_000875
• KDa
  56 kDa
• Vial with antibody
  Lyophilized
• Quantity per ml
  1 mg/ml
• NCBI GENE nr
  3615
• GENE symbol
  IMPDH2
• Antigene name
  IMP (inosine 5'-monophosphate) dehydrogenase 2
• Source
  Homo sapiens
• Protein nr
  P12268
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  IMPDH2  
• Gene symbol
  IMPDH2
• Short name
  anti-IMPDH2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toIMP (inosine 5'-monophosphate) dehydrogenase 2 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  IMP (inosine 5'-monophosphate) dehydrogenase 2, IMPD2 and IMPDH-II, IMPDH2 and IDBG-34157 and ENSG00000178035 and 3615, N-acylglucosamine-6-phosphate 2-epimerase activity, nuclei, Impdh2 and IDBG-200174 and ENSMUSG00000062867 and 100042069,23918, IMPDH2 and IDBG-646058 and ENSBTAG00000031837 and 511969

Gene info

• Identity
  HGNC:6053
• Gene
  IMPDH2
• Long gene name
  inosine monophosphate dehydrogenase 2
• Synonyms gene name
  • IMP (inosine 5'-monophosphate) dehydrogenase 2
• Locus
  3p21.31
• Discovery year
  1992-12-08
• Entrez gene record
  3615
• Pubmed identfication
  • 9858805
  • 1969416
• VEGA ID
  OTTHUMG00000156771

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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