ICA1 Antibody, ALEXA FLUOR 594
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Catalog numberbs-11349R-A594
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Price:
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Size100ul
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Long nameICA1 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
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Also known asAnti-ICA1 PAb ALEXA FLUOR 594
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CategoryConjugated Primary Antibodies
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Conjugated withALEXA FLUOR® 594
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Host OrganismRabbit (Oryctolagus cuniculus)
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Target AntigenICA1
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SpecificityThis is a highly specific antibody against ICA1.
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ModificationUnmodified
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Modification SiteNone
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ClonalityPolyclonal
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ClonePolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human ICA1
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Tested applicationsIF(IHC-P)
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Recommended dilutionsIF(IHC-P)(1:50-200)
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CrossreactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigenCarbonic anhydrases (CAs), also designated carbonate dehydratases or carbonate hydrolyases, form a large family of genes that encode zinc metalloenzymes of great physiologic importance. As catalysts of the reversible hydration of carbon dioxide, these enzymes participate in a variety of biologic processes, including respiration, acid-base balance, bone resorption and calcification as well as the formation of aqueous humor, cerebrospinal fluid, saliva and gastric acid. Genes in the ?carbonic anhydrase family encode either active carbonic anhydrase isozymes or æ³catalytic?(devoid of CO2 hydration activity) carbonic anhydrase-related proteins. Human CA I (CA1) is encoded by the CA1 gene, which maps to a region on chromosome 8 that harbors a cluster of CA genes. CA I localizes to the cytoplasm and research indicates that a severe deficiency of CA I does not result in any obvious hematological or renal consequences.
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PurificationPurified by Protein A.
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Storage conditionsStore this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission590nm/617nm
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Synonyms69 kDa islet cell autoantigen; Diabetes mellitus type I autoantigen; ICA 1; ICA1; ICA69; ICA69_HUMAN; ICAp69; Islet cell autoantigen 1 69kD; Islet cell autoantigen 1 69kDa; Islet cell autoantigen 1; Islet cell autoantigen 1 isoform; Islet cell autoantigen p69; OTTHUMP00000200933; OTTHUMP00000200934; OTTHUMP00000200941; OTTHUMP00000200993; p69.
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PropertiesFor facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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ConjugationAlexa Fluor, ALEXA FLUOR® 594
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ConjugatedAlexa conjugate 1
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French translationanticorps
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Gene target
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Gene symbolICA1-AS1, ICA1
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Short nameAnti-ICA1
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 594
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Alternative nameICA1 Polyclonal Antibody, ALEXA FLUOR 594
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Alternative techniqueantibodies
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Alternative to gene targetislet cell autoantigen 1, 69kDa, ICA69 and ICAp69, ICA1 and IDBG-8551 and ENSG00000003147 and 3382, protein domain specific binding, Cell surfaces, Ica1 and IDBG-128452 and ENSMUSG00000062995 and 15893, BT.35115 and IDBG-629525 and ENSBTAG00000000799 and 535346
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Gene info
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Identity
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Gene
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Long gene nameICA1 antisense RNA 1
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Locus
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Discovery year2021-06-09
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Entrez gene record
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RefSeq identity
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Classification
- Antisense RNAs
Gene info
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Identity
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Gene
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Long gene nameislet cell autoantigen 1
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Synonyms gene name
- islet cell autoantigen 1 (69kD)
- islet cell autoantigen 1, 69kDa
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Synonyms
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Locus
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Discovery year1992-08-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- AH domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data