HtrA2/Omi Antibody
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Catalog number3497-100
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PricePlease ask
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Size100 µg
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Antibody TargetHTRA2/OMI
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Target Alternative NameHTRA2 , HtrA2 , PARK13 , OMI , PRSS25
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Antibody TypePolyclonal
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Species ReactivitiesHuman, mouse, rat
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Immunogen SequenceRecombinant human HtrA2/Omi
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AccessionO43464
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Gene Id27429
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AppearanceColorless liquid
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FormLiquid
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Concentration0.5 mg/ml
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Formulation100 µg (0.5 mg/ml) antigen affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 50% glycerol, 1% BSA, and 0.02% thimerosal.
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PurificationAffinity purified
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ApplicationWestern blot, Immunofluorescence
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Application And UsagesWestern blotting (1-2 µg/ml) and immunofluorescence (20 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes the full length and the mitochondria-processed HtrA2/Omi.
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DescriptionHuman HtrA2 (also designated Omi) is a novel member of the HtrA serine protease family and is highly homologous to HtrA (also known as L56 and HtrA1). HtrA2 is ubiquitously expressed nuclear protease that is capable of autoproteolysis. The HtrA2 protein exists as two polypeptides of 38 and 40 kDa and as an alternatively spliced form called D-Omi, which is predominately expressed in the kidney, colon and thyroid. Like HtrA, HtrA2 is involved in the degradation aberrantly folded proteins during conditions of cellular stress, sμggesting that it may possess a chaperone-like role under normal conditions.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedNot Verified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolHTRA2
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Short nameHtrA2/Omi Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameHtrA serine peptidase 2/Omi (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetHtrA serine peptidase 2, HTRA2 and IDBG-57753 and ENSG00000115317 and 27429, unfolded protein binding, nuclei, Htra2 and IDBG-159586 and ENSMUSG00000068329 and 64704, HTRA2 and IDBG-631258 and ENSBTAG00000020124 and 523039
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Gene info
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Identity
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Gene
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Long gene nameHtrA serine peptidase 2
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Synonyms gene
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Synonyms gene name
- protease, serine, 25
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Synonyms
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Locus
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Discovery year2001-09-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PDZ domain containing
- Serine proteases
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data