Anti-HSPB1 (KO validated) Antibody
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Catalog numberA2074-100
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Price:
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Size100 µl
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Antibody TargetHSPB1
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Target Alternative NameHSPB1; CMT2F; HEL-S-102; HMN2B; HS.76067; HSP27; HSP28; Hsp25; SRP27
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Antibody TypePolyclonal
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Species ReactivitiesRat,Mouse,Human
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Immunogen SequenceRecombinant fusion protein targeting a sequence corresponding to aa 1-120 of human HSPB1
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AccessionP04792
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Gene Id3315
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AppearanceColorless liquid
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FormLiquid
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FormulationIn PBS with 0.02% sodium azide, 50% glycerol, pH 7.3
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PurificationAffinity purified
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ApplicationImmunohistochemistry (IHC),Immunofluorescence (IF),Western Blotting
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Application And UsagesWB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200
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DescriptionThis gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.
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Storage Condition-20ºC
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Shipping ConditionGel Pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedTrue
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Immunocytochemistry VerifiedFalse
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Immunofluorescence VerifiedTrue
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Immunoprecipitation VerifiedFalse
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FACS VerifiedFalse
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ELISA VerifiedFalse
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ChIP VerifiedFalse
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Dot Blot VerifiedFalse
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Flow Cytometry VerifiedFalse
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Additional descriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolHSPB1
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Short nameAnti-HSPB1 (KO validated) Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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IsotypeIgG
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Alternative nameAntibody toHSPB1 (KO validated) (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetheat shock 27kDa protein 1, CMT2F and HEL-S-102 and HMN2B and HS.76067 and Hsp25 and HSP27 and HSP28 and SRP27, HSPB1 and IDBG-23058 and ENSG00000106211 and 3315, poly(A) RNA binding, nuclei, Hspb1 and IDBG-204151 and ENSMUSG00000004951 and 15507, HSPB1 and IDBG-640144 and ENSBTAG00000011969 and 516099
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Gene info
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Identity
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Gene
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Long gene nameheat shock protein family B (small) member 1
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Synonyms gene name
- heat shock 27kD protein 1
- heat shock 27kDa protein 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-07-09
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Entrez gene record
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Pubmed identfication
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Classification
- Small heat shock proteins
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data