Glutaredoxin 1 Antibody (Clone 28C3)

• Catalog number
  6211-100
• Price
  Please ask
• Size
  100 μl

• Antibody Target
  Glutaredoxin 1
• Target Alternative Name
  Thioltransferase-1, GLRX, GRX
• Antibody Type
  Monoclonal
• Clone
  Clone 28C3
• Species Reactivities
  Human
• Immunogen Sequence
  Recombinant human protein purified from E.coli
• Accession
  P35754
• Gene Id
  2745
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  1 mg/ml
• Formulation
  100 µl of antibody in HEPES with 0.15 M NaCl, 0.01 % BSA, 0.03 % sodium azide, and 50 % glycerol
• Purification
  Ammonium sulphate precipitation
• Application
  IP, ELISA.
• Positive Control
  WB and IP: Jurkat cell lysate
• Application And Usages
  IP: 1-2 µl, ELISA.
• Description
  Glutaredoxin (Grx), also known as thiol transferase, is a small heat-stable oxidoreductase. Grxs form part of the glutaredoxin system, comprising NADPH, GSH and glutathione reductase, which transfers electrons from NADPH to glutaredoxins via GSH. First recovered in E.coli as GSH-dependent hydrogen donors for ribonucleotide reductase, Grx catalyzes GSH-disulfide oxido-reductase via two redox-active cysteine residues. The active sequence (Cys-Pro-Tyr-Cys) is conserved in a variety of species. The 12 kDa dithiol protein has a role in reduction of mixed disulfides in cells exposed to oxidative stress. Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Glutaredoxin   28C3  
• Short name
  Glutaredoxin 1 Antibody (Clone 28C3)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Mouse IgG1
• Alternative name
  Glutaredoxin 1 (antibody to-) (clonality 28C3)
• Alternative technique
  antibodies
• Clone name
  28C3

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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