anti-FAM193B Antibody

  • Catalog number
    6941
  • Price
    Please ask
  • Size
    0.02 mg, 0.1 mg
  • Gene info
    FAM193B Antibody: FAM193B, also known as IRIZIO, was initially identified as a protein that is upregulated in alveolar rhabdomyosarcoma (ARMS), a type of fast-growing tumor characterized by chromosomal translocations fusing the PAX3 or PAX7 gene with that of FOXO1. It has been suggested that, in addition to the PAX3-FOXO1 gene fusion, disruption of the Rb and p53 pathways is required for full ARMS tumorigenesis. In PAX3-FOXO1-expressing primary mouse fibroblasts that possessed a defective p53 pathway, FAM193B expression enabled the tumorigenic transformation, suggesting that FAM193B may contribute to rhabdomyosarcomagenesis in humans.
  • Gene names
    FAM193B Antibody: IRIZIO, KIAA1931, Protein FAM193B
  • Antibodie s label
    unlabelled serum
  • Purity
    FAM193B Antibody is affinity chromatography purified via peptide column.
  • Ab raised in
    Rabbit
  • Type
    Polyclonal
  • Immunoglobulin
    IgG
  • Spicific to
    At least two isoforms of FAM193B are known to exist; this antibody will detect both isoforms.
  • Antigen
    FAM193B antibody was made against a 16 amino acid synthetic peptide near the amino terminus of human FAM193B.
  • Immuno application
    ELISA, Western Blot, immuno fluorescence
  • Antibody advice
    FAM193B antibody can be used for detection of FAM193B by Western blot at 1 ug/mL. For immunofluorescence start at 20 ug/mL.
  • Suspention pH azide
    FAM193B Antibody is supplied in PBS containing 0.02% sodium azide.
  • Keep at
    FAM193B antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • Works with
    Human
  • Omim nr
    205831282
  • Ncbi nr
    Q96PV7
  • KDa
    99 kDa
  • Vial with antibody
    in solution
  • Quantity per ml
    1 mg/mL
  • NCBI GENE nr
    54540
  • GENE symbol
    FAM193B
  • Antigene name
    family with sequence similarity 193, member B
  • Source
    homo sapiens
  • Protein nr
    Q96PV7
  • Description
    This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
  • Properties
    If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    FAM193B  
  • Gene symbol
    FAM193B-DT, FAM193B
  • Short name
    anti-FAM193B Antibody
  • Technique
    Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
  • Alternative name
    Antibody toFAM193B (antibody to-)
  • Alternative technique
    antibodies
Gene info
  • Identity
  • Gene
  • Long gene name
    FAM193B divergent transcript
  • Locus
  • Discovery year
    2020-08-21
  • Entrez gene record
  • Classification
    • Divergent transcripts
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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