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Target antigen
EBAG9
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Clonality
Polyclonal antibody
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Clone
Polyclonal antibody
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Raised in
rabbit
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Type of the antibody
IgG polyclonal antibody
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Product form
freeze-dried
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Reacts with species
human, mouse, rat
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Analyses
WB,IHC-P
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Immunogen
E.coli-derived human EBAG9 recombinant protein (Position: R31-S213). Human EBAG9 shares 97.8% and 94.5% amino acid (aa) sequence identity with mouse and rat EBAG9, respectively.
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Product configuration
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
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Purification
Immunogen affinity purified.
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Solubilization
The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtions
Keep the EBAG9 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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Tips
The EBAG9 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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Background
Receptor-binding cancer antigen expressed on SiSo cells is a protein that in humans is encoded by the EBAG9 gene. This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor, which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. And the encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10.
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Related articles
1. "Entrez Gene: EBAG9 estrogen receptor binding site associated, antigen, 9". 2. Ikeda K; Sato M; Tsutsumi O et al. (2000). "Promoter analysis and chromosomal mapping of human EBAG9 gene". Biochem. Biophys. Res. Commun. 273 (2): 654–60. 3. Tsuneizumi M; Emi M; Nagai H et al. (2002). "Overrepresentation of the EBAG9 gene at 8q23 associated with early-stage breast cancers". Clin. Cancer Res. 7 (11): 3526–32.
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Gene Name
EBAG9
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Protein Name
Receptor-binding cancer antigen expressed on SiSo cells
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Gene Full Name
estrogen receptor binding site associated, antigen, 9
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Synonyms
BAG9 antibody|Cancer associated surface antigen antibody|Cancer associated surface antigen RCAS1 antibody|Cancer-associated surface antigen RCAS1 antibody|EB9 antibody|EBAG 9 antibody|EBAG9 antibody|Estrogen receptor binding fragment associated gene 9 protein antibody|Estrogen receptor binding site associated antigen 9 antibody|estrogen receptor binding site associated, antigen, 9 antibody|Estrogen receptor-binding fragment-associated gene 9 protein antibody|PDAF antibody|RCAS 1 antibody|RCAS1 antibody|RCAS1_HUMAN antibody| Receptor binding cancer antigen expressed on SiSo cells antibody|Receptor-binding cancer antigen expressed on SiSo cells antibody
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Uniprot ID
O00559
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Entrez GeneID
9166
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Properties
If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
