CITED2 Antibody (NT)
-
Catalog number5286-100
-
PricePlease ask
-
Size100 µg
-
-
Antibody TargetCITED2
-
Target Alternative NameCbp/p300-interacting transactivator 2, melanocyte-specific gene 1-related gene 1, MSG-related protein 1, MRG1, melanocyte specific gene 2, MSG2, ER154-like, ASD8, VSD2
-
Antibody TypePolyclonal
-
Species ReactivitiesHuman, mouse, rat
-
Immunogen SequenceCITED2 antibody was raised against an 18 amino acid peptide near the amino terminus of human CITED2.
-
AccessionQ99967
-
Gene Id10370
-
AppearanceColorless liquid
-
FormLiquid
-
Concentration1 mg/ml
-
Formulation100 µg (1 mg/ml) in 1X PBS containing 0.02 % sodium azide.
-
PurificationAffinity chromatography purified via peptide column
-
ApplicationWestern blot, ELISA
-
Positive ControlWestern Blot: Jurkat cell lysate
-
Application And UsagesWestern Blot: 1 - 2 μg/ml, ELISA. However, the optimal conditions should be determined individually.
-
DescriptionCITED2 was initially identified as a potential transcriptional activator with significant homology to MSG1, a melanocyte-specific nuclear protein. CITED2 interacts with the histone acetyltransferase p300/CBP and acts as a coactivator to several DNA-binding transcription factors such as HIF-1 and AP-2. CITED2 also controls proliferation of mouse embryonic fibroblasts via the polycomb group genes Bmi-1 and Mel18 and the tumor suppressor Ink4a/Arf. CITED2 has also been found to be an essential regulator of adult hematopoietic stem cells (HSCs), with conditional deletion of CITED2 in the adult mouse resulting in the loss of HSCs, multilineage bone marrow failure and increased lethality.
-
Storage Condition-20 °C
-
Shipping Conditiongel pack
-
Shelf Life12 months
-
UsageFor Research Use Only! Not to be used in humans.
-
HandlingThe antibody solution should be gently mixed before use.
-
Western Blot VerifiedVerified
-
Immunocytochemistry VerifiedNot Verified
-
Immunofluorescence VerifiedNot Verified
-
Immunoprecipitation VerifiedNot Verified
-
FACS VerifiedNot Verified
-
ELISA VerifiedVerified
-
ChIP VerifiedNot Verified
-
Flow Cytometry VerifiedNot Verified
-
PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolCITED2
-
Short nameCITED2 Antibody (NT)
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
IsotypeRabbit IgG1
-
Alternative nameCbp/p300-interacting transactivator, including L-gutamic acid/L-aspartic acid-rich carboxy-terminal domain, 2 (antibody to-) (NT)
-
Alternative techniqueantibodies
-
Alternative to gene targetCbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2, ASD8 and MRG-1 and MRG1 and P35SRJ and VSD2, CITED2 and IDBG-97161 and ENSG00000164442 and 10370, LBD domain binding, nuclei, Cited2 and IDBG-134872 and ENSMUSG00000039910 and 17684, CITED2 and IDBG-633814 and ENSBTAG00000011224 and 521378
-
Gene info
-
Identity
-
Gene
-
Long gene nameCbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2
-
Synonyms gene name
- Cbp/p300-interacting transactivator, with Glu/Asp rich carboxy-terminal domain, 2
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year1999-06-11
-
Entrez gene record
-
Pubmed identfication
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data