CCR4 Antibody

• Catalog number
  PA1516
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  CCR4
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human, mouse, rat
• Analyses
  WB,IHC-P
• Immunogen
  A synthetic peptide corresponding to a sequence at the C-terminus of human CCR4(346-360aa SYTQSTMDHDLHDAL).
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the CCR4 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The CCR4 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  CCR4,C-C chemokine receptor type 4 is a protein that in humans is encoded by the CCR4 gene. CCR4 has also recently been designated CD194(cluster of differentiation 194). The protein encoded by this gene belongs to the G protein-coupled receptor family. It is a receptor for the following CC chemokines. The CCR4 gene is mapped to chromosome 3. Chemokines are a group of small structurally related proteins that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
• Related articles
  1. Imai, T., Baba, M., Nishimura, M., Kakizaki, M., Takagi, S., Yoshie, O.The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4.J. Biol. Chem. 272: 15036-15042, 1997. 2. Imai, T., Chantry, D., Raport, C. J., Woods, C. L., Nishimura, M., Godiska, R., Yoshie, O., Gray, P. W.Macrophage-derived chemokine is a functional ligand for the CC chemokine receptor 4.J. Biol. Chem. 273: 1764-1768, 1998. 3. Oo, Y. H., Weston, C. J., Lalor, P. F., Curbishley, S. M., Withers, D. R., Reynolds, G. M., Shetty, S., Harki, J., Shaw, J. C., Eksteen, B., Hubscher, S. G., Walker, L. S. K., Adams, D. H.Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver.J. Immun. 184: 2886-2898, 2010.
• Gene Name
  CCR4
• Protein Name
  C-C chemokine receptor type 4(C-C CKR-4/CC-CKR-4/CCR-4/CCR4)
• Gene Full Name
  chemokine(C-C motif) receptor 4
• Synonyms
  C C chemokine receptor type 4 antibody|C C CKR 4 antibody|C-C chemokine receptor type 4 antibody|C-C CKR-4 antibody|CC CKR 4 antibody|CC-CKR-4 antibody|CCR 4 antibody|CCR-4 antibody|CCR4 antibody|CCR4_HUMAN antibody|CD194 antibody|Chemokine(CC motif) receptor 4 antibody|chemokine C C motif receptor 4 antibody|ChemR13 antibody|CKR4 antibody|CMKBR 4 antibody|CMKBR4 antibody|HGCN 14099 antibody|K5 5 antibody|K5-5 antibody|MGC88293 antibody
• Uniprot ID
  P51679
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CCR4  
• Gene symbol
  CNOT6, CCR4
• Short name
  CCR4 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  chemokine (C-C motif) receptor 4 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  chemokine (C-C motif) receptor 4, CC-CKR-4 and CD194 and ChemR13 and CKR4 and CMKBR4 and HGCN:14099 and K5-5, CCR4 and IDBG-23908 and ENSG00000183813 and 1233, C-C chemokine receptor activity, Cell surfaces, Ccr4 and IDBG-203512 and ENSMUSG00000047898 and 12773, CCR4 and IDBG-644121 and ENSBTAG00000034883 and 100851774,408019

Gene info

• Identity
  HGNC:14099
• Gene
  CNOT6
• Long gene name
  CCR4-NOT transcription complex subunit 6
• Synonyms gene name
  • CCR4-NOT transcription complex, subunit 6
• Synonyms
  • CCR4
  • KIAA1194
  • Ccr4a
• GenBank acession
  • AB033020
• Locus
  5q35.3
• Discovery year
  2001-03-30
• Entrez gene record
  57472
• Pubmed identfication
  • 11889047
• RefSeq identity
  • NM_015455
• Classification
  • CCR4-NOT transcription complex
• VEGA ID
  OTTHUMG00000130935

Gene info

• Identity
  HGNC:1605
• Gene
  CCR4
• Long gene name
  C-C motif chemokine receptor 4
• Synonyms gene name
  • chemokine (C-C motif) receptor 4
• Synonyms
  • CC-CKR-4
  • CMKBR4
  • CKR4
  • k5-5
  • ChemR13
  • CD194
• GenBank acession
  • X85740
• Locus
  3p22.3
• Discovery year
  1996-05-15
• Entrez gene record
  1233
• Pubmed identfication
  • 7642634
  • 8884276
• Classification
  • C-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000130752

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products