anti-ARID1A Antibody
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Catalog number8173
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Price:
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Size0.02 mg, 0.1 mg
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Gene infoThe ARID1A protein is a member of the SWI/SNF family, whose members are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. ARID1A is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin (1). It possesses a DNA-binding domain that can specifically bind an AT-rich DNA sequence known to be recognized by a SNF/SWI complex at the beta-globin locus. The C-terminus of the protein can stimulate glucocorticoid receptor-dependent transcriptional activation. It is thought that ARID1A confers specificity to the SNF/SWI complex and may recruit the complex to its targets through either protein-DNA or protein-protein interactions (2).
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Gene namesAT rich interactive domain 1A (SWI-like), RP1-50O24.1, B120, BAF250, BAF250a, BM029, C1orf4, ELD, hELD, MRD14, OSA1, hOSA1, P270, SMARCF1
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Antibodie s labelunlabelled serum
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PurityARID1A antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toARID1A antibody is human, mouse and rat reactive. Multiple isoforms of ARID1A protein are known to exist.
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AntigenARID1A antibody was made against an 18 amino acid peptide near the amino terminus of human ARID1A.
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Immuno applicationELISA, Western Blot
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Antibody adviceARID1A antibody can be used for detection of ARID1A by Western blot at 1 - 2 ug/ml.
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Suspention pH azideARID1A antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atARID1A antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
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Works withHuman, Mouse, Rat
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Omim nr21264565
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Ncbi nrNP_006006
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KDaPredicted: 133, 227, 251 kDa Observed: 130, 260 kDa
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr8289
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GENE symbolARID1A
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Antigene nameAT rich interactive domain 1A (SWI-like)
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Sourcehomo sapiens
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Protein nrO14497
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolARID1A
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Short nameanti-ARID1A Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toARID1A (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameAT-rich interaction domain 1A
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Synonyms gene
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Synonyms gene name
- SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily f, member 1
- AT rich interactive domain 1A (SWI- like)
- AT rich interactive domain 1A (SWI-like)
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-06-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BAF complex
- Armadillo like helical domain containing
- AT-rich interaction domain containing
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data