Annexin VIII Antibody
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Catalog number3637R-30T
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PricePlease ask
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Size30 µg
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Antibody TargetAnnexin A8
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Target Alternative NameANXA7 , ANX7 , SNX , Annexin A7
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Antibody TypePolyclonal
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Species ReactivitiesHuman
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Immunogen SequenceSynthetic peptide surrounding amino acid 316 of human Annexin VIII
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AccessionP13928
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Gene Id653145
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AppearanceColorless liquid
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FormLiquid
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Concentration0.5 mg/ml
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Formulation30 µg (0.5 mg/ml) protein A purified rabbit anti-Annexin VIII polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
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ApplicationWestern blot, Immunohistochemistry
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Positive ControlWestern Blot: Jurkat cell lysate. IHC: Placenta tissue
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Application And UsagesWestern blotting (0.5-4 µg/ml) and Immunohistochemistry (5 µg/ml) . However, the optimal conditions should be determined individually. Jurkat cell lysate (Cat.# 2401-100) can be used as a positive control. The antibody detects 36 kDa annexin VIII of human origin. The ~28-30 kDa cleavage fragments can also be detected in Jurkat cell lysate
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DescriptionThe annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain which binds to phospholipids in a Ca2+-dependent manner. Annexin family members have been implicated as regulators of diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. Annexin VIII is preferentially expressed in acute promyelocytic leukemia (APL) cells which may relate its role in hematopoietic cell differentiation.
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Storage Condition-20 °C
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Shipping Conditiongel pack
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Shelf Life12 months
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UsageFor Research Use Only! Not to be used in humans.
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HandlingThe antibody solution should be gently mixed before use.
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Western Blot VerifiedVerified
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Immunocytochemistry VerifiedVerified
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Immunofluorescence VerifiedNot Verified
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Immunoprecipitation VerifiedNot Verified
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FACS VerifiedNot Verified
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ELISA VerifiedNot Verified
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ChIP VerifiedNot Verified
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Flow Cytometry VerifiedNot Verified
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Additional descriptionThis Annexin V calcium dependent phospholipid binding protein will be downstream of BCL2 pathway and at caspase apoptotic level. Biovision has more cell death kits and antibodies.
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PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolCOX8A, G3BP1, MARCHF8
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Short nameAnnexin VIII Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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IsotypeRabbit IgG
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Alternative nameAnnexin VIII (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namecytochrome c oxidase subunit 8A
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Synonyms gene
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Synonyms gene name
- cytochrome c oxidase subunit VIII
- cytochrome c oxidase subunit VIIIA (ubiquitous)
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Synonyms
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GenBank acession
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Locus
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Discovery year1989-06-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Mitochondrial complex IV: cytochrome c oxidase subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameG3BP stress granule assembly factor 1
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Synonyms gene name
- GTPase activating protein (SH3 domain) binding protein 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2006-10-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- RNA binding motif containing
- Endoribonucleases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemembrane associated ring-CH-type finger 8
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Synonyms gene
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Synonyms gene name
- c-mir, cellular modulator of immune recognition
- membrane-associated ring finger (C3HC4) 8
- membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
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Synonyms
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GenBank acession
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Locus
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Discovery year2003-11-12
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ring finger proteins
- Membrane associated ring-CH-type fingers
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data