anti-Akirin2 Antibody

• Catalog number
  4805
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  Akirin2 Antibody: The highly conserved, nuclear-localized Akirin1 and Akirin2 proteins critically regulate the transcription of NF-kB-dependent genes and are required for defense against Gram-negative bacteria in the immune deficiency and NF-kB pathways. Akirin1 is dispensable in the mouse, and neither knockout mice nor cells derived from them have obvious distinctive phenotypes. In contrast, Akirin2 is required for development in the mouse and knockout of both Akirin homologs in mice show that Akirin2 is required downstream of toll-like receptor (TLR), TNF-a; and IL-1β signaling, and for the production of IL-6. Akirin2 is functionally closer to the single gene in Drosophila, as the homozygous null D. melanogaster Akirin mutants show a similar, mid-to-early embryonic death.
• Gene names
  Akirin2 Antibody: FBI1, C6orf166, dJ486L4.2, Akirin-2
• Antibodie s label
  unlabelled serum
• Purity
  Akirin2 Antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  Akirin2 antibody was made against a 15 amino acid synthetic peptide near the center of the human Akirin2.
• Immuno application
  ELISA, Western Blot
• Antibody advice
  Akirin2 antibody can be used for detection of Akirin2 by Western blot at 0.5 ug/mL.
• Suspention pH azide
  Akirin2 Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  Akirin2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human, Mouse, Rat
• Omim nr
  119568963
• Ncbi nr
  EAW48578
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  55122
• GENE symbol
  AKIRIN2
• Antigene name
  akirin 2
• Source
  Homo sapiens
• Protein nr
  Q53H80
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Akirin2  
• Gene symbol
  AKIRIN2
• Short name
  anti-Akirin2 Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toakirin 2 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  akirin 2, AKIRIN2 and IDBG-94215 and ENSG00000135334 and 55122, enzyme binding, nuclei, Akirin2 and IDBG-134912 and ENSMUSG00000028291 and 433693, AKIRIN2 and IDBG-632578 and ENSBTAG00000003764 and 614292

Gene info

• Identity
  HGNC:21407
• Gene
  AKIRIN2
• Long gene name
  akirin 2
• Synonyms gene
  • C6orf166
• Synonyms gene name
  • chromosome 6 open reading frame 166
• Synonyms
  • FLJ10342
  • dJ486L4.2
• GenBank acession
  • BC000764
• Locus
  6q15
• Discovery year
  2003-06-12
• Entrez gene record
  55122
• Pubmed identfication
  • 19200367
• RefSeq identity
  • NM_018064
• VEGA ID
  OTTHUMG00000015180

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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