anti-ADRM1 Antibody
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Catalog number8119
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PricePlease ask
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Size0.02 mg, 0.1 mg
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Gene infoThe adhesion-regulating molecule 1 (ADRM1) is thought to be involved in protein recruitment and cell adhesion and functions as a proteasomal ubiquitin receptor (1). ADRM1 promotes the activity of UCH-L5 and plays a role in lymphocyte homing. The carboxy-terminal domain of mammalian ADRM1 serves to bind and enhance the isopeptidase activity of UCHL5/UCH37, perhaps serving as a mechanism to accelerate ubiquitin chain disassembly (2,3). ADRM1 expression is induced by IFN-gamma in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis (4,5).
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Gene namesAdhesion regulating molecule 1, ARM1, Gp110, hRpn13, Proteasomal ubiquitin receptor ADRM1, Proteasome regulatory particle non-ATPase 13, Rpn13
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Antibodie s labelunlabelled serum
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PurityADRM1 antibody is affinity chromatography purified via peptide column.
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Ab raised inRabbit
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TypePolyclonal
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ImmunoglobulinIgG
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Spicific toADRM1 antibody is human, mouse and rat reactive. At least two isoforms of ADRM1 are know to exist; this antibody will detect both isoforms.
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AntigenADRM1 antibody was made against a 19 amino acid peptide near the center of human ADRM1.
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Immuno applicationELISA, Western Blot, immuno-histo-chemistry
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Antibody adviceADRM1 antibody can be used for detection of ADRM1 by Western blot at 1 - 2 ug/mL. Antibody can also be used for immunohistochemistry starting at 5 ug/mL.
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Suspention pH azideADRM1 antibody is supplied in PBS containing 0.02% sodium azide.
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Keep atADRM1 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
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Works withHuman, Mouse, Rat
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Omim nr28373194
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Ncbi nrNP_783163
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KDaPredicted: 45 kDa Observed: 48 kDa
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Vial with antibodyin solution
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Quantity per ml1 mg/mL
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NCBI GENE nr11047
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GENE symbolADRM1
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Antigene nameadhesion regulating molecule 1
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Sourcehomo sapiens
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Protein nrQ16186
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolADRM1
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Short nameanti-ADRM1 Antibody
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toadhesion regulating molecule 1 (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetadhesion regulating molecule 1, ARM-1 and ARM1 and GP110, ADRM1 and IDBG-84373 and ENSG00000130706 and 11047, proteasome binding, nuclei, ADRM1 and IDBG-640954 and ENSBTAG00000003058 and 519729
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Gene info
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Identity
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Gene
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Long gene nameADRM1 26S proteasome ubiquitin receptor
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Synonyms gene name
- adhesion regulating molecule 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-09-17
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Entrez gene record
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Pubmed identfication
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Classification
- Proteasome
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data