AMG 232 for cell activation

AMG 232 for cell activation is available 2 times from Biovision labs

9556-5 | AMG-232 for cell activationsize: 5 mg | 468.57 USD

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9556-1 | AMG-232 for cell activationsize: 1 mg | 161.29 USD

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  • Description
    AMG232 is a highly potent MDM2 inhibitor (SPR KD = 0.045 nM, SJSA-1 EdU IC₅₀ = 9.1 nM), with remarkable pharmacokinetic properties and in vivo antitumor activity in the SJSA-1 osteosarcoma xenograft model (ED₅₀ = 9.1 mg/kg).
  • Peptide sequence
    N/A
  • CAS number
    1352066-68-2
  • Molecular weight
    568.55
  • Category
    Biochemicals
  • Other name
    2-[(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-[(2S)-3-methyl-1-propan-2-ylsulfonylbutan-2-yl]-2-oxopiperidin-3-yl]acetic acid
  • Molecular formula
    C₂₈H₃₅Cl₂NOS
  • Physical appearance
    Crystalline solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO (>5 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    AMG-232 for activation
  • Technique
    activation
  • Alternative name
    AMG-232 to measure cellular activation
  • Tissue
    cell
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