AMACR Antibody

• Catalog number
  bs-0840R
• Price
  Please ask
• Size
  0.1ml

• Long name
  AMACR Primary Polyclonal Antibody
• Also known as
  AMACR PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  AMACR
• Specificity
  This is a highly specific antibody against AMACR.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic peptide derived from mouse AMACR
• Gene ID number
  23600
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  alpha-methylacyl-CoA racemase(AMACR/P504S) is Prostate-specific antigen (PSA) screening for prostate cancer is now widespread in the United States among men of all ages. However PSA has limited specificity because benign disease, including prostatic enlargement and inflammation, can increase PSA levels. Thus, a more specific prostate cancer markers is needed. One such potential marker is AMACR, an enzyme that is involved in peroxisomal beta-oxidation of dietary branched-chain fatty acids. Recent studies have shown that, compared with expression in normal or benign prostate epithelium, AMACR is consistently overexpressed in prostate cancer epithelium, making it a specific marker for cancer cells within the prostate gland. Furthermore, overexpression of AMACR may increase the risk of prostate cancer because its expression is increased in premalignant lesions (prostatic intraepithelial neoplasia).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  2 arylpropionyl CoA epimerase; 2 methylacyl CoA racemase; 2-methylacyl-CoA racemase; Alpha methylacyl-CoA racemase deficiency, included; Alpha-methylacyl-CoA racemase; alpha-methylacyl-CoA racemase isoform 1; P504S; Amacr; AMACR; AMACR deficiency, included; CBAS4; P504S; RACE; 2 arylpropionyl CoA epimerase; Alpha methylacyl Coenzyme A racemase; Alpha methylacyl CoA racemase; AMACR_HUMAN; EC 5.1.99.4; Da1-8; RACE; RM; Macr 1; Macr1; Methylacyl CoA racemase alpha.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  AMACR  
• Gene symbol
  C1QTNF3-AMACR, AMACR
• Short name
  Anti-AMACR
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  AMACR Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:49198
• Gene
  C1QTNF3-AMACR
• Long gene name
  C1QTNF3-AMACR readthrough (NMD candidate)
• Locus
  5p13.2
• Discovery year
  2013-09-30
• Entrez gene record
  100534612
• VEGA ID
  OTTHUMG00000186337

Gene info

• Identity
  HGNC:451
• Gene
  AMACR
• Long gene name
  alpha-methylacyl-CoA racemase
• Synonyms
  • RACE
  • P504S
• GenBank acession
  • AF047020
• Locus
  5p13.2
• Discovery year
  1999-10-19
• Entrez gene record
  23600
• Pubmed identfication
  • 9307041
• RefSeq identity
  • NM_014324
• VEGA ID
  OTTHUMG00000090734

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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