ABT 869 for cell activation

ABT 869 for cell activation is available 2 times from Biovision labs

1615-1 | ABT-869 for cell activationsize: 1 mg | 250.68 USD

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1615-5 | ABT-869 for cell activationsize: 5 mg | 724.97 USD

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  • Description
    ABT-869 is multi-targeted inhibitor of all members of the VEGF and PDGF receptor families (e.g., KDR, IC₅₀ value of 4 nM), but has much less activity (IC₅₀ values >1 µM) against unrelated receptor tyrosine kinases, soluble tyrosine kinases or serine/threonine kinases. The kinase inhibition profile of ABT-869 is evident in cellular assays of RTK phosphorylation (IC₅₀ values of 2, 4 and 7 nM for PDGFRβ, KDR and CSF-1R, respectively) and VEGF-stimulated proliferation (0.2 nM IC₅₀ for human endothelial cells).
  • Peptide sequence
    N/A
  • CAS number
    796967-16-3
  • Molecular weight
    375.41
  • Category
    Biochemicals
  • Other name
    Linifanib
  • Molecular formula
    C₂₁H₁₈FN₅O
  • Physical appearance
    Crystalline solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥99%
  • Reconstitute instructions
    DMSO
  • Storage condition
    -20°C
  • Shipping condition
    RT
  • Maximum time for storage
    24months
  • Storage instructions
    Protect from air and moisture
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    ABT-869 for activation
  • Technique
    activation
  • Alternative name
    ABT-869 to measure cellular activation
  • Tissue
    cell
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