ABI2 Antibody
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Catalog numberPA2068
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Price:
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Size0,1 mg
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Target antigenABI2
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ClonalityPolyclonal antibody
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ClonePolyclonal antibody
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Raised inrabbit
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Type of the antibodyIgG polyclonal antibody
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Product formfreeze-dried
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Reacts with specieshuman Predicted to work with: mouse, rat
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AnalysesWB
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ImmunogenA synthetic peptide corresponding to a sequence at the N-terminus of human ABI2(158-173aa RFKVSTQNMKMGGLPR), identical to the related mouse and rat sequences.
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Product configurationEach vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
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PurificationImmunogen affinity purified.
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SolubilizationThe powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
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Storage condtionsKeep the ABI2 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
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TipsThe ABI2 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
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BackgroundABI2(ABL Interactor 2), is a protein that in humans is encoded by the ABI2 gene. By analysis of a YAC and a BAC, Machado et al.(2000) mapped the ABI2 gene to 2q31-q33. ABI2 possesses a basic N terminus with homology to a homeodomain protein; a central serine-rich region; 3 PEST sequences, which are implicated in susceptibility to protein degradation; several proline-rich stretches; and an acidic C terminus with multiple phosphorylation sites and an SH3 domain. Dai and Pendergast(1995) suggested that the ABI proteins may function to coordinate the cytoplasmic and nuclear functions of the ABL1 tyrosine kinase.
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Related articles1. Dai, Z., Pendergast, A. M. Abi-2, a novel SH3-containing protein interacts with the c-Abl tyrosine kinase and modulates c-Abl transforming activity. Genes Dev. 9: 2569-2582, 1995. 2. Machado, R. D., Pauciulo, M. W., Fretwell, N., Veal, C., Thomson, J. R., Guell, C. V., Aldred, M., Brannon, C. A., the International PPH Consortium, Trembath, R. C., Nichols, W. C. A physical and transcript map based upon refinement of the critical interval for PPH1, a gene for familial primary pulmonary hypertension. Genomics 68: 220-228, 2000.
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Gene NameABI2
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Protein NameAbl interactor 2
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Gene Full Nameabl-interactor 2
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SynonymsAbelson interactor 2 antibody|ABI 2 antibody|ABI2B antibody|Abl binding protein 3 antibody|Abl interacting protein 1(SH3 containing protein) antibody|Abl interactor 2 antibody|Abl interactor protein 2b antibody|AblBP3 antibody|AIP 1 antibody|Arg binding protein 1 antibody|Arg protein tyrosine kinase binding protein antibody|ArgBP1 antibody|ARGBPIA antibody|ArgBPIB antibody|OTTHUMP00000163783 antibody|OTTHUMP00000163784 antibody|OTTHUMP00000206182 antibody|OTTHUMP00000206183 antibody|OTTHUMP00000206184 antibody|OTTHUMP00000206185 antibody|SSH3BP2 antibody
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Uniprot IDQ9NYB9
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PropertiesIf you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolABI2
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Short nameABI2 Antibody
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TechniqueAntibody, antibodies against human proteins, antibodies for
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Alternative nameABI2 (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameabl interactor 2
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Synonyms gene name
- abl-interactor 2
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-03-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SCAR/WAVE complex
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data