3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib-d3

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Cas number

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Chemical s molecular weight

449.92
Chemical s main applications

3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib-d3 is the isotope labelled analog of 3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib (D289540); an impurity of Gefitinib (G304000) which is a tyrosine kinase inhibitor that targets the epidermal growth factor receptor (EGFR).
Chemical s category

Amines, Aromatics, Heterocycles, Isotope Labelled Compounds, Pharmaceuticals, Intermediates & Fine Chemicals
Other name

N-(4-Chloro-3-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine-d3
Chemical s formula

C22H21D3ClFN4O3
Physical properties

No Data Available
Melting temperature

No Data Available
Boiling temperature

No Data Available
Chemical s soluble in

No Data Available
Stability conditions

No Data Available
Storage

No Data Available
Chemical s specifications

Gene target

3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib-d3
Gene symbol

MIR1302-4, PIRC18, TRP-TGG3-4, PIRC16, SNORD114-4, TRK-TTT3-4, MIR941-4, IGKV2OR2-4
Short name

3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib-d3
Alternative name

3-Deschloro-4-desfluoro-4-chloro-3-fluoro Gefitinib-d3

Identity

HGNC:34956
Gene

TRP-TGG3-4
Long gene name

tRNA-Pro (anticodon TGG) 3-4
Synonyms gene
- TRNAP21
- TRP-TGG3-3
Synonyms gene name
- transfer RNA proline 21 (anticodon UGG)
- transfer RNA-Pro (TGG) 3-3
- transfer RNA-Pro (TGG) 3-4
Synonyms
- tRNA-Pro-TGG-3-4
GenBank acession
- HG983999
Locus

16p13.3
Discovery year

2008-08-29
Entrez gene record

100189388
Classification
- Cytoplasmic transfer RNAs

Identity

HGNC:33256
Gene

TRK-TTT3-4
Long gene name

tRNA-Lys (anticodon TTT) 3-4
Synonyms gene
- TRNAK3
- TRK-TTT3-3
Synonyms gene name
- transfer RNA lysine 3 (anticodon UUU)
- transfer RNA-Lys (TTT) 3-3
- transfer RNA-Lys (TTT) 3-4
Synonyms
- tRNA-Lys-TTT-3-4
GenBank acession
- HG983933
Locus

11q12.1
Discovery year

2007-02-01
Entrez gene record

100049613
Pubmed identfication
- 3678837
Classification
- Cytoplasmic transfer RNAs

Identity

HGNC:5809
Gene

IGKV2OR2-4
Long gene name

immunoglobulin kappa variable 2/OR2-4 (pseudogene)
Synonyms gene name
- immunoglobulin kappa variable 2/OR2-4
- immunoglobulin kappa variable 2/OR2-4 pseudogene
Synonyms
- IGKV2/OR2-4
GenBank acession
- X51883
Locus

2q11.2
Discovery year

2000-04-18
Entrez gene record

28858
Pubmed identfication
- 2111145
Classification
- Immunoglobulin kappa (IGK) orphons