1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone
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Catalog number
D461960
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Price
Please ask
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Size
100 mg
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Chemical available in other sizes
Please inquire size and price
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Stock availability
Pending QC
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Cas number
1253056-01-7
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Chemical s molecular weight
408.3
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Chemical s main applications
1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985), which is an impurity of Sitagliptin (S491000); a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
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Chemical s formula
C16H14F6N4O2
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Physical properties
Off-White Solid
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Melting temperature
No Data Available
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Boiling temperature
No Data Available
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Chemical s soluble in
Acetone, Dichloromethane, Methanol
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Stability conditions
No Data Available
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Storage
No Data Available
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Gene target
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Short name
1-[5 6-Dihydro-3-(trifluoromethyl)-1 2 4-triazolo[4 3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2 4 5-trifluorophenyl)-1-butanone
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Alternative name
1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-3-hydroxy-4-(2,4,5-trifluorophenyl)-1-butanone
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MeSH Data
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Name
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Concept
Scope note:
An in vitro allergen radioimmunoassay in which allergens are coupled to an immunosorbent. The coupled allergens bind the IgE in the sera of patients which in turn binds radioisotope-labeled anti-IMMUNOGLOBULIN E antibodies.
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Tree numbers
- E01.370.225.812.735.830
- E05.200.812.735.830
- E05.478.566.380.810
- E05.478.566.639.810
- E05.478.594.760.830
- E05.601.470.380.810
- E05.601.470.639.810
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Qualifiers
ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data
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