MCA (human) - Clone b-12

Synonym

pan-Mucin Producing Cells
StorageTemperature

+5 ± 3 °C
HOST

Mouse
Clone

b-12
Format

Purified, Lyophilized
Species Crossreactivity

human
Application

IHC
Conjugate

NA
Top Categories

Antibodies
Keywords

Monoclonal; primary antibody
Additonal Description

b-12 is useful for identifying human mucin-like carcinoma antigen (MCA) produced by various tumors and certain healthy glandular cells. In combination with other markers for inflammation staging or investigating neo-vascularization processes, b-12 is a valuable tool for studying tumor growth or regression. MCA is a 350 kD glycoprotein with the typical biochemical characteristics of mucin-like glycoproteins (sialomucins) which protect surfaces. Antibody b-12 binds to the protein backbone of MCA, not to the large number of carbohydrate side chains. Application: IHC (f, p)
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Identity

HGNC:27570
Gene

MILR1
Long gene name

mast cell immunoglobulin like receptor 1
Synonyms gene
- C17orf60
Synonyms gene name
- chromosome 17 open reading frame 60
- mast cell immunoglobulin-like receptor 1
Synonyms
- Allergin-1
- MCA-32
Synonyms name
- allergy inhibitory receptor 1
- mast cell antigen 32
GenBank acession
- BC053534
Locus

17q23.3
Discovery year

2005-12-16
Entrez gene record

284021
Pubmed identfication
- 20526344
RefSeq identity
- NM_001085423
Classification
- Immunoglobulin like domain containing
VEGA ID

OTTHUMG00000185198