Macrophage Scavenger Receptor (mouse) - Clone 2F8
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Catalog number
T-2123.0250
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Price
Please ask
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Size
250ug
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Synonym
CD204
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StorageTemperature
+5 ± 3 °C
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HOST
Rat
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Clone
2F8
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Format
Purified IgG from tissue culture supernatant, Liquid
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Species Crossreactivity
mouse
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Application
IHC, FACS, IP,ELISA, WB
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Conjugate
NA
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Top Categories
Antibodies
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Keywords
Monoclonal; primary antibody
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Additonal Description
2F8 recognizes the murine scavenger receptor types I and II on tissue macrophages. It inhibits the uptake of acetylated LDL as well as divalent cation independent adhesion. Application: IHC (f), FACS, Immunoprecipitation, ELISA, Western Blot
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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