HLA II (human) - Clone HKB1
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Catalog numberT-1361.0200
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PricePlease ask
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Size200ug
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StorageTemperature+5 ± 3 °C
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HOSTMouse
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CloneHKB1
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FormatPurified, lyophilized
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Species Crossreactivityhuman
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ApplicationIHC, FACS
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ConjugateNA
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Top CategoriesAntibodies
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KeywordsMonoclonal; primary antibody
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Additonal DescriptionMarker for human leukocyte antigen class II. Monoclonal antibody HKB1 recognizes all HLA class II antigens, the 3 major (HLA-DP, -DQ and -DR) and 2 minor major histocompatibility complex MHC class II proteins (HLA-DM and -DO). The genes of the class II combine to form heterodimeric (? ?) protein receptors that are typically expressed on the surface of antigen presenting cells (APCs): dendritic cells, B-cells, and macrophages. HLA class II is presented on activated T-cells. HLA class II molecules present exogenously derived antigen to the T-cell receptor (TCR) on CD4? T lymphocytes. Application: IHC (f), FACS
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Gene target
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Gene symbolHLA-DPA2, HLA-DOA, HLA-DQA1, HLA-N, HLA-DQA2, HLA-DPB1, HLA-DQB2, HLA-W, HLA-DRA, HLA-S
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Short nameHLA II ( ) - Clone HKB1
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IsotypeIgM
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SpeciesHuman, Humans
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Alternative nameHuman leukocyte antigen II (H. sapiens) - clonality HKB1
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Clone nameHKB1
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Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class II, DP alpha 2 (pseudogene)
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Synonyms gene
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class II, DO alpha
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C1-set domain containing
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class II, DQ alpha 1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- C1-set domain containing
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class I, N (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-10-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
-
Gene
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Long gene namemajor histocompatibility complex, class II, DQ alpha 2
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Synonyms gene
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- C1-set domain containing
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class II, DP beta 1
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Synonyms gene
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- C1-set domain containing
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class II, DQ beta 2
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Synonyms gene
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GenBank acession
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Locus
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Discovery year2001-06-22
-
Entrez gene record
-
Pubmed identfication
-
Classification
- C1-set domain containing
- Histocompatibility complex
-
VEGA ID
-
Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class I, W (pseudogene)
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Synonyms gene
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Synonyms gene name
- HLA-80 pseudogene
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GenBank acession
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Locus
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Discovery year2004-01-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class II, DR alpha
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Synonyms gene
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Locus
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Discovery year2001-06-22
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Entrez gene record
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RefSeq identity
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Classification
- C1-set domain containing
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class I, S (pseudogene)
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-10-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Testing erythrocytes to determine presence or absence of blood-group antigens, testing of serum to determine the presence or absence of antibodies to these antigens, and selecting biocompatible blood by crossmatching samples from the donor against samples from the recipient. Crossmatching is performed prior to transfusion.
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Tree numbers
- E01.370.225.625.120
- E01.370.225.812.385.120
- E05.200.625.120
- E05.200.812.385.120
- E05.478.594.385.120
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Qualifiersethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data