CMKLR1 (mouse) - Clone 1G10

Synonym

G Protein-coupled Receptor DEZ, ChemR23, Chemokine-like Receptor 1
StorageTemperature

+5 ± 3 °C
HOST

Rat
Clone

1G10
Format

Purified IgG from tissue culture supernatant, Liquid
Species Crossreactivity

mouse
Application

IHC
Conjugate

NA
Top Categories

Antibodies
Keywords

Monoclonal; primary antibody
Additonal Description

UniProt: P97468 Monoclonal antibody 1G10 recognizes the G protein-coupled receptor CMKLR1, a member of the seven-transmembrane domain receptors. CMKLR1 is a 371 amino acid protein that binds the chemoattractant adipokine chemerin / RARRES2 and the omega-3 fatty acid-derived molecule resolvin E1. Binding of the agonist leads to multifunctional effects, like reduction of immune responses, enhancing of adipogenesis and angionesis. This receptor has been described to be expressed in immature plasmacytoid dendritic cells (DCs) and, at lower levels, in myeloid DCs, macrophages, and NK cells. Expression has also been described on macrophages isolated from different tissues.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus

Gene target

CMKLR1 1G10
Gene symbol

CMKLR1
Short name

CMKLR1 (mouse) - Clone 1G10
Technique

Mouse, mouses
Host

mouse
Isotype

IgG
Species

Mouse, Mouses
Alternative name

chemokine-like receptor 1 (mouse) - clonality 1G10
Alternative technique

murine
Alternative to gene target

chemokine-like receptor 1, CHEMERINR and ChemR23 and DEZ and RVER1, CMKLR1 and IDBG-55274 and ENSG00000174600 and 1240, protein binding, Plasma membranes, Cmklr1 and IDBG-191760 and ENSMUSG00000042190 and 14747, CMLKR1 and IDBG-647886 and ENSBTAG00000022039 and 615411
Clone name

1G10