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Synonym
CD88, C5a Anaphylatoxin Chemotactic Receptor
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StorageTemperature
+5 ± 3 °C
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HOST
Mouse
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Clone
3C6
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Format
Protein G purified; lyophilized
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Species Crossreactivity
human
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Application
IHC
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Conjugate
NA
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Top Categories
Antibodies
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Keywords
Monoclonal; primary antibody
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Additonal Description
UniProt: P21730 C5aR is a 350 amino acid, 45kDa member of the G protein-coupled receptor 1 family (GPCR) that interacts with C5a with very high binding affinity and, to a lesser extent, with C5a-desArg. It is a seven-membrane-spanning receptor found on neutrophils (PMN) and macrophages, and on a variety of other cell types such as endothelial cells, alveolar epithelial cells and Kupffer cells. C5aR is biochemically and apparently also functionally different from the other receptor for C5a, C5L2 (please see: T- 1218 GPR77 (human) - Clone 1A6).
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
