Apelin Receptor (mouse, rat) - Polyclonal
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Catalog number
T-2304.0200
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Price
Please ask
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Size
200ug
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StorageTemperature
+5 ± 3 °C
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HOST
Chicken
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Clone
N/A
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Format
Purified, Lyophilized
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Species Crossreactivity
mouse, rat
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Application
IHC
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Conjugate
NA
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Top Categories
Antibodies
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Keywords
Polyclonal; primary antibody
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Additonal Description
Apelin seems to be involved in the regulation of circadian rhythms and of water and food intake behaviour. The apelin receptor is widely expressed, notably in the lung but also in heart and several structures in the brain. The antibody was generated against the extracellular amino-terminal portion of the apelin receptor. Application: IHC (f, p)
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus, Rattus norvegicus
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
APLNR, APELA
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Short name
Apelin Receptor (mouse, ) - Polyclonal
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Technique
Polyclonal, Mouse, mouses, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Host
mouse
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Isotype
IgY
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Species
Rat, Mouses, Rats
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Alternative name
Apelin Receptor (mouse, rat) - polyclonal
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Alternative technique
polyclonals, murine
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Gene info
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Identity
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Gene
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Long gene name
apelin receptor
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Synonyms gene
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Synonyms gene name
- angiotensin II receptor-like 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1994-07-07
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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