ABri (human) - Polyclonal

• Catalog number
  T-1516.0200
• Price
  Please ask
• Size
  200ug

• StorageTemperature
  +5 ± 3 °C
• HOST
  Chicken
• Clone
  N/A
• Format
  Purified, Liquid
• Species Crossreactivity
  human
• Application
  IHC
• Conjugate
  NA
• Top Categories
  Antibodies
• Keywords
  Polyclonal; primary antibody
• Additonal Description
  This antibody has been developed against the mutated version of Bri (see T-1515) called ABri. The unusual extension of Bri by 34 amino acids is cleaved by the protease furin. The ensuing 4 kD peptide contributes to the deposition of insoluble amyloid fibrils in the brain, leading to the pathology of familial British dementia. The antibody was developed against the carboxy-terminal portion of ABri, recognizing the mutated ABri as well as the cleaved 34 amino acids containing peptide. Application: Western Blot Amyloid Bri Peptide (1-34) is a Bachem catalog product (H-4728).
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

• Gene target
  ABri  
• Short name
  ABri ( ) - Polyclonal
• Technique
  Polyclonal, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  IgY
• Species
  Human, Humans
• Alternative name
  ABri (H. sapiens) - polyclonal
• Alternative technique
  polyclonals

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