Recombinant Human T-cell immunoreceptor with Ig and ITIM domains/TIGIT (C-Fc)

• Catalog number
  CS92-50
• Price
  Please ask
• Size
  50 ug

• Description
  Recombinant Human T-cell Immunoreceptor With Ig and ITIM Domains is produced by our Mammalian expression system and the target gene encoding Met22-Pro141 is expressed with a Fc tag at the C-terminus.
• Species reactivity
  Human
• Origin
  Human cells
• Peptide sequence
  MMTGTIETTGNISAEKGGSIILQCHLSSTTAQVTQVNWEQQDQLLAICNADLGWHISPSFKDRVAPGPGLGLTLQSLTVNDTGEYFCIYHTYPDGTYTGRIFLEVLESSVAEHGARFQIPIEGRMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
• Estimated molecular weight
  39.7
• Protein purity
  Greater than 95% as determined by reducing SDS-PAGE.
• Endotoxin level
  Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
• Shipping condition
  Ambient/Room Temperature
• Package form
  Lyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
• Storage conditions
  Lyophilized protein should be stored at below -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at below -20°C for 3 months.
• Reconstitution conditions
  Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 µg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• UniProt number
  Q495A1
• Other related products
• Additional description
  For cells, cell lines and tissues in culture till half confluency.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  immunoreceptor   with   ITIM   domains/TIGIT   C-Fc  
• Gene symbol
  TIGIT
• Short name
  Recombinant T- immunoreceptor with Ig ITIM domains/TIGIT (C-Fc)
• Technique
  Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Recombinant Human TIGIT (C-Fc)
• Alternative technique
  rec
• Alternative to gene target
  T cell immunoreceptor with Ig and ITIM domains, TIGIT and IDBG-50851 and ENSG00000181847 and 201633, protein binding, Cell surfaces, Tigit and IDBG-161101 and ENSMUSG00000071552 and 100043314, TIGIT and IDBG-632631 and ENSBTAG00000011921 and 100140801
• Tissue
  cell

Gene info

• Identity
  HGNC:26838
• Gene
  TIGIT
• Long gene name
  T cell immunoreceptor with Ig and ITIM domains
• Synonyms gene
  • VSIG9
  • VSTM3
• Synonyms gene name
  • VSIG9, VSTM3
• Synonyms
  • FLJ39873
  • DKFZp667A205
• GenBank acession
  • AK097192
• Locus
  3q13.31
• Discovery year
  2006-02-07
• Entrez gene record
  201633
• Pubmed identfication
  • 19011627
• RefSeq identity
  • NM_173799
• Classification
  • V-set domain containing
• VEGA ID
  OTTHUMG00000159331

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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