Recombinant Human Interleukin-18-Binding Protein/IL18BP (C-Fc)

• Catalog number
  CB99-500
• Price
  Please ask
• Size
  500 ug

• Description
  Recombinant Human IL-18 binding protein is produced by our Mammalian expression system and the target gene encoding Thr31-Gly194 is expressed with a Fc tag at the C-terminus.
• Species reactivity
  Human
• Origin
  Human cells
• Peptide sequence
  TPVSQTTTAATASVRSTKDPCPSQPPVFPAAKQCPALEVTWPEVEVPLNGTLSLSCVACSRFPNFSILYWLGNGSFIEHLPGRLWEGSTSRERGSTGTQLCKALVLEQLTPALHSTNFSCVLVDPEQVVQRHVVLAQLWAGLRATLPPTQEALPSSHSSPQQQGVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSREEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
• Estimated molecular weight
  44,7 kDa
• Protein purity
  Greater than 95% as determined by reducing SDS-PAGE.
• Endotoxin level
  Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
• Shipping condition
  Ambient/Room Temperature
• Package form
  Lyophilized from a 0.2 µm filtered solution of 20mM PB,150mM NaCl,pH7.2.
• Storage conditions
  Lyophilized protein should be stored at below -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at below -20°C for 3 months.
• Reconstitution conditions
  See included datasheet or contact us for more information.
• UniProt number
  O95998
• Other related products
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Interleukin-18-Binding   Protein/IL18BP   C-Fc  
• Gene symbol
  IL18BP, SNORD114-18, PIRC96, SNORD116-18, IGLV2-18, IGHV1-18, SNORD115-18, ERVW-18, IGKV2D-18
• Short name
  Recombinant Interleukin-18-Binding Protein/IL18BP (C-Fc)
• Technique
  Recombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Human IL-18 binding protein/IL-18BP(C-Fc)
• Alternative technique
  rec
• Alternative to gene target
  interleukin 18 binding protein, IL18BPa, IL18BP and IDBG-62960 and ENSG00000137496 and 10068, receptor anta this GO nist activity, Extracellular, Il18bp and IDBG-202395 and ENSMUSG00000070427 and 16068, IL18BP and IDBG-634897 and ENSBTAG00000027676 and 617470

Gene info

• Identity
  HGNC:5987
• Gene
  IL18BP
• Long gene name
  interleukin 18 binding protein
• Synonyms
  • IL18BPa
• Synonyms name
  • MC51L-53L-54L homolog gene product
• GenBank acession
  • AF110798
• Locus
  11q13.4
• Discovery year
  1999-05-21
• Entrez gene record
  10068
• Pubmed identfication
  • 10023777
• RefSeq identity
  • NM_173042
• Classification
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000133713

Gene info

• Identity
  HGNC:33006
• Gene
  SNORD114-18
• Long gene name
  small nucleolar RNA, C/D box 114-18
• Synonyms
  • 14q(II-18)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767596
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003211.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:37600
• Gene
  PIRC96
• Long gene name
  piwi-interacting RNA cluster 96
• Locus
  18
• Discovery year
  2009-11-05
• Entrez gene record
  100313800
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:33084
• Gene
  SNORD116-18
• Long gene name
  small nucleolar RNA, C/D box 116-18
• Synonyms
  • HBII-85-18
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033430
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003333
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:5889
• Gene
  IGLV2-18
• Long gene name
  immunoglobulin lambda variable 2-18
• GenBank acession
  • Z73642
• Locus
  22q11.22
• Discovery year
  2000-05-08
• Entrez gene record
  28814
• RefSeq identity
  • NG_000002
• Classification
  • Immunoglobulin lambda locus at 22q11.2
• VEGA ID
  OTTHUMG00000151232

Gene info

• Identity
  HGNC:5549
• Gene
  IGHV1-18
• Long gene name
  immunoglobulin heavy variable 1-18
• GenBank acession
  • M99641
• Locus
  14q32.33
• Discovery year
  2000-04-04
• Entrez gene record
  28468
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152276

Gene info

• Identity
  HGNC:33037
• Gene
  SNORD115-18
• Long gene name
  small nucleolar RNA, C/D box 115-18
• Synonyms
  • HBII-52-18
• GenBank acession
  • AF250841
• Locus
  15q11.2
• Discovery year
  2007-02-15
• Entrez gene record
  100033456
• Pubmed identfication
  • 11106375
  • 11726556
• RefSeq identity
  • NR_003310.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:49306
• Gene
  ERVW-18
• Long gene name
  endogenous retrovirus group W member 18
• Synonyms gene name
  • endogenous retrovirus group W, member 18
• GenBank acession
  • HG421056
• Locus
  6q24.2
• Discovery year
  2013-10-21

Gene info

• Identity
  HGNC:5794
• Gene
  IGKV2D-18
• Long gene name
  immunoglobulin kappa variable 2D-18 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2D-18
  • immunoglobulin kappa variable 2D-18 pseudogene
• GenBank acession
  • X63395
• Locus
  2p11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28888
• RefSeq identity
  • NG_000833
• Classification
  • Immunoglobulin kappa locus at 2p11.2
• VEGA ID
  OTTHUMG00000151620

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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