Recombinant Human Fibroblast Growth Factor Receptor 3/FGF R3 (C-Fc)
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Catalog numberCB43-1000
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PricePlease ask
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Size1 mg
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DescriptionRecombinant Human Fibroblast Growth Factor Receptor 3 is produced by our Mammalian expression system and the target gene encoding Glu23-Gly375 is expressed with a Fc tag at the C-terminus.
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Species reactivityHuman
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OriginHuman Cells
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Peptide sequenceESLGTEQRVVGRAAEVPGPEPGQQEQLVFGSGDAVELSCPPPGGGPMGPTVWVKDGTGLVPSERVLVGPQRLQVLNASHEDSGAYSCRQRLTQRVLCHFSVRVTDAPSSGDDEDGEDEAEDTGVDTGAPYWTRPERMDKKLLAVPAANTVRFRCPAAGNPTPSISWLKNGREFRGEHRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSIRQTYTLDVLERSPHRPILQAGLPANQTAVLGSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGIEGRMDPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
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Estimated molecular weight64,8 kDa
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Protein purityGreater than 95% as determined by reducing SDS-PAGE.
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Endotoxin levelLess than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
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Shipping conditionAmbient/Room Temperature
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Package formLyophilized from a 0.2 µm filtered solution of PBS, pH7.4.
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Storage conditionsLyophilized protein should be stored at below -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at below -20°C for 3 months.
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Reconstitution conditionsSee included datasheet or contact us for more information.
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UniProt numberP22607
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Additional descriptionAplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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SourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolFGF18, FGF17, NUDT6, FGF4, FGF1
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Short nameRecombinant Fibroblast Growth Factor Receptor 3/FGF R3 (C-Fc)
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TechniqueRecombinant, FC, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHuman, Humans
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Alternative nameRecombinant Human FGF R3 (C-Fc)
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene namefibroblast growth factor 18
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibroblast growth factor family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namefibroblast growth factor 17
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-12-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibroblast growth factor family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenudix hydrolase 6
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Synonyms gene name
- nudix (nucleoside diphosphate linked moiety X)-type motif 6
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Synonyms
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GenBank acession
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Locus
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Discovery year1999-09-03
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Nudix hydrolase family
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namefibroblast growth factor 4
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Synonyms gene
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Synonyms gene name
- heparin secretory transforming protein 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1988-04-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibroblast growth factor family
- Receptor ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namefibroblast growth factor 1
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Synonyms gene
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Synonyms gene name
- fibroblast growth factor 1 (acidic)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibroblast growth factor family
- Receptor ligands
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data