RAGE (human AGE Receptor)

  • Catalog number
    RAGE05
  • Price
    Please ask
  • Size
    50 mcg
  • Clone
    1C5
  • Species Reactivity
    Human, other species not determined
  • Product Types
    Primary Antibodies
  • Positive Control
    Diabetic kidney, arteriosclerosis
  • Immunogen
    Recombinant protein, soluble receptor human RAGE
  • Working Concentration
    (liquid conc.) 0.1 µg/ml WB, 1 µg/ml ICC, 1 µg/ml FACS, 0.01 µg/ml ELISA
  • Concentration
    250 µg/ml
  • Incubation Time
    60 min at RT or 18 hr at 2-8°C
  • Application
    IHC, WB
  • Storage
    -20°C
  • UniProt
    Q15109 (RAGE_HUMAN)
  • Properties
    Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
  • Description
    The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
  • Gene target
    RAGE   AGE   Receptor  
  • Gene symbol
    AGER, MOK
  • Short name
    RAGE ( AGE Receptor)
  • Host
    Mouse
  • Isotype
    IgG1,k
  • Species
    Human, Humans
  • Alternative name
    RAGE (H. sapiens AGE Receptor)
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