EGF Receptor

Clone

111.6
Species Reactivity

Human, not reactive in mouse and rat
Product Types

Primary Antibodies
Positive Control

Mamma carcinoma
Immunogen

Extracellular domain of human EGFR
Working Concentration

(liquid conc.) 1:10-1:25
Concentration

50 µg/ml
Incubation Time

60 min at RT
Application

IHC(C, P), IP, WB
Storage

2-8°C
UniProt

NA
Description

The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

Gene target

EGF Receptor
Gene symbol

EGF
Short name

EGF Receptor
Host

Mouse
Isotype

IgG1
Alternative name

epidermal growth factor Receptor
Alternative to gene target

epidermal growth factor, HOMG4 and URG, EGF and IDBG-34100 and ENSG00000138798 and 1950, transmembrane receptor protein tyrosine kinase activator activity, Extracellular, Egf and IDBG-193432 and ENSMUSG00000028017 and 13645