Collagen Type I, human

Clone

NA
Species Reactivity

Human, cross-reactivity with cattle
Product Types

Primary Antibodies
Positive Control

Human skin
Immunogen

Purified collagen type I from human skin
Working Concentration

(liquid conc.) IFA 1:80, IHC(P) 1:200 - 1:600, ELISA >1:200 (OD>500)
Concentration

app. 1 mg/ml
Incubation Time

IHC(P) 60 min at RT or 2-8°C over night
Application

IHC(P), IFA, ELISA, RIA, IB/WB
Storage

-20°C
UniProt

P02452 (CO1A1_HUMAN); P08123 (CO1A2_HUMAN)
Gene

Collagen Types in bones and muscles can be hydrolyzed and used in human grafts. ( Type II )
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Identity

HGNC:2198
Gene

COL1A2
Long gene name

collagen type I alpha 2 chain
Synonyms gene
- OI4
Synonyms gene name
- osteogenesis imperfecta type IV
- collagen, type I, alpha 2
- collagen type I alpha 2
Synonyms name
GenBank acession
- Z74616
Locus

7q21.3
Discovery year

2001-06-22
Entrez gene record

1278
Pubmed identfication
- 3857213
- 2897363
RefSeq identity
- NM_000089
Classification
- Collagens
VEGA ID

OTTHUMG00000148675
Locus Specific Databases
- Osteogenesis Imperfecta Variant Database
- LRG_2