Sphingomyelin Synthase 2 - Blocking Peptide

• Catalog number
  X2060B
• Price
  Please ask
• Size
  50 μg

• Category
  Proteins & Peptides
• Long description
  Sphingomyelin (SM) is a major component of animal plasma membranes. Its production involves the transfer of phosphocholine from phosphatidylcholine and then onto ceramide. This also yields diacylglycerol as a side product. The reaction is catalysed by SM synthase, an important enzyme in the regulation of diacylglycerol and ceramide as anti- and proapoptotic stimuli. SM synthesis occurs in the lumen of the Golgi as well as on or at the cell surface. It is uncertain which SM enzyme forms are present at these differnet cellular locations. Human, mouse and Caenorhabditis elegans genomes each contain at least two different SM synthase (SMS) genes. Human SMS1 is localised to the Golgi, SMS2 resides primarily at the plasma membrane.
• Antibody come from
  Synthetic peptide derived from the human ACAD11 protein
• Other description
  Provided as solution in phosphate buffered saline with 0.08% sodium azide.
• Clone
  not specified
• Antigen antibody binding interaction
  Sphingomyelin Synthase 2 - Blocking Peptide
• Antibody is raised in
  see techfile
• Antibody s reacts with
  see techfile
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Western Blot
• Antibody s suited for
  Antibody can be used for Western blotting (1-5 µg/ml starting dilution). Optimal concentration should be evaluated by serial dilutions.
• Storage
  -20ºC
• Relevant references
  1. He, M, et al. Identification and characterization of new long chain acyl-CoA dehydrogenases. Mol. Genet. Metab. 2011, 102, 418-429
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Test
  You can block the antibody by the specific target amino acid sequence of peptide.
• Properties
  blocking peptide
• Description
  Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.

• Gene target
  Sphingomyelin   Synthase  
• Gene symbol
  SGMS2
• Short name
  Sphingomyelin Synthase 2 - Blocking Peptide
• Technique
  blocking peptide, Blocking, peptide, blocking peptides, nordc made this blocking amino acid sequence or peptide to block the gene target in a volume of 1. For western blot it is often requested to block your antibody and to see the band of the analyzed protein disappear. This is called a negative control by blocking the WB antibody. peptides
• Isotype
  not specified
• Label
  unlabeled
• Alternative name
  Sphingomyelin Synthase 2 - inhibiting short protein sequence
• Alternative technique
  control, peptides

Gene info

• Identity
  HGNC:28395
• Gene
  SGMS2
• Long gene name
  sphingomyelin synthase 2
• Synonyms
  • MGC26963
  • SMS2
• GenBank acession
  • BC041369
• Locus
  4q25
• Discovery year
  2007-03-15
• Entrez gene record
  166929
• Pubmed identfication
  • 14685263
• RefSeq identity
  • NM_152621
• VEGA ID
  OTTHUMG00000131811

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