Rabbit anti Protein Tyrosine Phosphatase Mu (PTPRM)
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Catalog number
X2264P
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Price
Please ask
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Size
50 μg
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Category
Primary Antibodies
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Long description
PTP mu, a R2A receptor protein tyrosine phosphatase, is composed of an extracellular segment containing a MAM domain, an immunoglobulin domain and four fibronectin type III repeats, a transmembrane segment, and two intracellular protein phosphatase domains. PTP mu has been shown to affect cell-cell aggregation, regulate cardiac myocyte Kv1.5 channel expression, and promote neurite outgrowth of retinal ganglion cells. The human PTP mu gene is localized on chromosome 18pter-q11, a region with frequent abnormalities implicated in human cancer. PTP mu may be important in responses to pathological conditions associated with the loss of cell-cell interactions in the heart._x000B__x000B__x000B_
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Antibody come from
internal domain of human
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Other description
Phosphate buffered saline containing 0.1% sodium azide. Immunoaffinity Purification
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Clone
Polyclonal
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Antigen antibody binding interaction
Rabbit anti Protein Tyrosine Phosphatase Mu (PTPRM) Antibody
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Antibody is raised in
Rabbit
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Antibody s reacts with
Human
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Antibody s reacts with these species
This antibody doesn't cross react with other species
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Antibody s specificity
No Data Available
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Application
Immunohistochemistry
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Antibody s suited for
Antibody can be used for immunohistochemistry on formalin-fixed, paraffin-embedded tissues (10 µg/ml). Optimal concentration should be evaluated by serial dilutions.
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Storage
Long term: -70ºC; Short term: +4ºC
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Relevant references
no information yet
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Protein number
see ncbi
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Warnings
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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About
Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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Gene target
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Gene symbol
PTPRM
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Short name
Rabbit anti Protein Tyrosine Phosphatase Mu (PTPRM)
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Technique
Rabbit, anti, antibody to
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Host
Rabbit, Rabbits
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Isotype
not specified
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Label
unlabeled
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Alternative name
production species: rabbit antibody to Protein Tyrosine Phosphatase Mu (protein tyrosine phosphatase, receptor classification, M)
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Alternative technique
rabbit-anti, antibodies
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Alternative to gene target
protein tyrosine phosphatase, receptor type, M, hR-PTPu and PTPRL1 and R-PTP-MU and RPTPM and RPTPU, PTPRM and IDBG-670 and ENSG00000173482 and 5797, cadherin binding, Cell surfaces, Ptprm and IDBG-195581 and ENSMUSG00000033278 and 19274, PTPRM and IDBG-644257 and ENSBTAG00000024015 and 536092
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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