Rabbit anti Protein Kinase antibody Lysine Deficient 1 (PRKWNK1)
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Catalog number
X2151P
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Price
Please ask
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Size
50 μg
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Category
Primary Antibodies
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Long description
WNK1, a WNK type protein kinase, contains a small N-terminal domain followed by a kinase domain and a long C-terminal tail. The protein is cytoplasmic and has been shown to regulate both the c-Jun N-terminal kinase pathway and the actin cytoskeleton in vitro. WNK1 has been identified as the gene mutant in pseudohypoaldosteronism type 2, also known as Gordon hyperkalemia-hypertension syndrome, which is a rare autosomal dominant form of volume-dependent, low-renin hypertension. Disease-causing mutations are large intronic deletions that increase WNK1 expression. At least two variants of WNK1 are produced by alternative splicing.
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Antibody come from
C-terminal domain of human
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Other description
Phosphate buffered saline containing 0.1% sodium azide. Immunoaffinity Purification
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Clone
Polyclonal
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Antigen antibody binding interaction
Rabbit anti Protein Kinase antibody Lysine Deficient 1 (PRKWNK1) Antibody
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Antibody is raised in
Rabbit
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Antibody s reacts with
Human
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Antibody s reacts with these species
This antibody doesn't cross react with other species
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Antibody s specificity
No Data Available
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Application
Immunohistochemistry
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Antibody s suited for
Antibody can be used for immunohistochemistry on formalin-fixed, paraffin-embedded tissues (20 µg/ml)._x000B_Optimal concentration should be evaluated by serial dilutions.
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Storage
Long term: -70ºC; Short term: +4ºC
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Relevant references
no information yet
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Protein number
see ncbi
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Warnings
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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Properties
If you buy Antibodies supplied by nordc they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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About
Rabbits are used for polyclonal antibody production by nordc. Rabbit antibodies are very stable and can be stored for several days at room temperature. nordc adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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French translation
anticorps
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Gene target
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Gene symbol
WNK1
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Short name
Rabbit anti Protein Kinase antibody Lysine Deficient 1 (PRKWNK1)
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Technique
Antibody, Rabbit, anti, antibody to, antibodies against human proteins, antibodies for
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Host
Rabbit, Rabbits
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Isotype
not specified
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Label
unlabeled
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Alternative name
production species: rabbit antibody to Protein phosphorylation catalyst (antibody to-) Lysine Deficient 1 (PRKWNK1)
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Alternative technique
antibodies, rabbit-anti
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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